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          neuropharamcology

          This shows neurons.
          FeaturedNeurologyNeuroscience
          ·November 19, 2025·7 min read

          Lithium Fails to Slow Cognitive Decline in Alzheimer’s

          A new meta-analysis of six randomized controlled trials shows that lithium supplementation does not significantly slow cognitive decline in people with mild cognitive impairment or Alzheimer’s disease. While preclinical evidence suggests lithium supports resilience against amyloid and tau pathology, these benefits failed to translate to clinical outcomes using traditional lithium salts.
          Read More
          This shows neurons.
          FeaturedNeurologyNeuroscience
          ·October 15, 2024·4 min read

          Mini Brains Uncover Treatment Leads for Lewy Body Dementia

          Lewy body dementia (LBD) is a challenging-to-diagnose neurodegenerative disease with symptoms similar to both Parkinson’s and Alzheimer’s diseases, including hallucinations, cognitive issues, and movement disorders. To study LBD’s progression, researchers developed mini brain models from LBD patient stem cells, replicating key disease characteristics seen in human brains. These models helped identify four promising drugs that may inhibit alpha-synuclein buildup, a key protein associated with LBD.
          Read More
          This shows diagrams from the study
          FeaturedNeurosciencePsychology
          ·March 6, 2022·2 min read

          How Long-Term Benzodiazepine Use Leads to Cognitive Impairments

          Mouse study reveals synaptic loss associated with a daily sleep-inducing dose of diazepam for several weeks leads to cognitive impairments. However, the effect was reversible after discontinuing benzodiazepine use.
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          This shows a head being erased by a pencil eraser
          FeaturedNeurologyNeuroscience
          ·January 19, 2022·5 min read

          Cholesterol Buildup in Brain Presents New Target to Reduce Dementia Risk From Stroke

          Cyclodextrin, an FDA-approved drug, reduced cholesterol accumulation from broken down brain cells and inflammation in animal models. The findings point to a potential new therapy to reduce dementia following a stroke.
          Read More
          This shows a brain scan from the study
          FeaturedNeuroscience
          ·September 27, 2021·5 min read

          Withdrawal From Psychostimulants Restructures Functional Architecture of Brain

          Withdrawal from psychostimulants including methamphetamines, cocaine, and nicotine, produced restructuring of brain regions and major increases in functional connectivity, a new mouse study reveals.
          Read More
          This shows hippocampal neurons
          FeaturedNeurosciencePsychology
          ·April 28, 2021·4 min read

          A Psychedelic-Like Drug Without the Hallucinogenic Side Effects

          PsychLight, a newly developed genetically encoded fluorescent sensor, helped researchers identify a psychedelic compound that acts on beneficial neural pathways to treat psychiatric disorders without the hallucinogenic effect.
          Read More
          This shows a bottle and dropper
          FeaturedNeurologyNeurosciencePain
          ·April 25, 2021·6 min read

          Research Shows Pain Relieving Effects of CBD

          CBD does not appear to reduce experimental pain intensity but does make the experience of pain less unpleasant.
          Read More
          This is a stick and ball model of dopamine
          FeaturedNeurologyOpen Neuroscience Articles
          ·July 15, 2020·5 min read

          Dopamine Therapy Improves Cognitive Function in Alzheimer’s

          Rotigotine, a drug that acts on dopamine transmission, improves cognitive function in patients with mild-to-moderate Alzheimer's disease. While the drug did not help improve memory, it did improve executive function in the frontal lobe and positively impacted the ability of patients to perform activities of daily living.
          Read More
          This is a diagram from the study
          FeaturedNeuroscience
          ·April 17, 2020·3 min read

          New nanocarrier drug delivery technology crosses the blood-brain barrier

          Researchers have developed a cyclic peptide that can enhance blood-brain barrier penetration.
          Read More
          This shows two heads
          FeaturedNeurologyNeuroscienceOpen Neuroscience Articles
          ·March 11, 2020·4 min read

          Common muscle relaxant given via nose shows potential to treat Alzheimer’s

          Dantrolene, a common muscle relaxant, shows promise in the treatment of Alzheimer's disease. Mice administered the drug intranasally had higher concentrations of the medicine in their brains, and for longer periods, than those who received it orally. The drug has been shown to help inhibit or slow the progression of several neurodegenerative diseases.
          Read More
          This shows an old man's hands
          FeaturedNeurologyNeuroscience
          ·January 16, 2020·3 min read

          Antipsychotics associated with increased risk of head & brain injuries in persons with Alzheimer’s disease

          Alzheimer's patients who used antipsychotics had a 29% increased risk of head injury and a 22% higher risk of TBI compared to others with the neurodegenerative disease who did not use the medications.
          Read More
          This shows the vet and a dog
          FeaturedNeurologyNeuroscience
          ·May 21, 2019·4 min read

          CBD clinical trial results on seizure frequency in dogs ‘encouraging’

          Dogs with epilepsy who received cannabidiol as part of a clinical trial had a reduction in the frequency of seizures.
          Read More
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          • AI Reveals Lions Don’t Just Roar, They Have a Second Call
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          This shows a lion roaring.

          AI Reveals Lions Don’t Just Roar, They Have a Second Call

          This shows a screaming child.

          What Triggers Tantrums? Sensory Overload May Be To Blame

          This shows a brain.

          Brain Circuit That Forces Behavior Into “Repeat Mode” Identified

          This shows a brain and DNA.

          Genetics Plus Heart Health Markers Sharpen Dementia Risk

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