Supplementing the amino acid D-serine helped to mitigate some of the age-related changes associated with a decline of the hypothalamic hormone Menin in mouse models.
The immune signaling molecule interleukin 1B (IL-1B) is present at higher levels in mouse models of alcohol use disorder. The IL 1B pathway plays a different role in animal models of AUD, causing inflammation in brain areas that play a critical role in decision-making.
Genes linked to inflammation, neurotransmission, and immunity act differently in the brains of those on the autism spectrum compared to neurotypical people. These differences begin during childhood and evolve throughout a person's lifespan.
Blocking the activity of the reactor called the aryl hydrocarbon receptor in T cells resulted in both a decrease in inflammation and recovery in mouse models of multiple sclerosis.
Cocaine use disorder alters gene expression in the nucleus accumbens and caudate nucleus, brain areas associated with reward, and the mediation of habit formation.
The Orai1 class of calcium channels regulates sex differences in the functioning of immune cells associated with neuroinflammation and neuropathic pain.
Levodopa, a drug commonly prescribed for the treatment of Parkinson's disease that increases dopamine in the brain was found to reverse the effects of neuroinflammation on the reward system and improve symptoms associated with depression.
Could a Viral Illness Increase Chances of Developing Alzheimer’s or Other Neurodegenerative Disease?
Study reveals a significant association between certain viral illnesses, including viral encephalitis and pneumonia-causing flu with an increased risk of developing a neurodegenerative disorder later in life. Researchers say existing vaccines against the viruses may reduce the chances of developing neurodegeneration.
Study sheds new light on the link between brain inflammation and cognitive impairment associated with aging. Findings suggest the connection may be the result of a cellular chain reaction.
High-fat diets promote early inflammatory responses in the brain via an immune pathway associated with diabetes and neurodegenerative diseases. The findings suggest a link between metabolic dysfunction and cognitive impairment.
Food allergens can affect your brain and behavior if you are hypersensitized, even if you don't suffer from typical food allergy symptoms.
COVID-19 infection activates the same inflammatory response in the brain as Parkinson's disease, a new study reports.
