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neuroinflammation

Featured Neurology Neuroscience Psychology

·November 27, 2023·5 min read

Alzheimer’s Neuropsychiatric Symptoms Linked to Brain Inflammation

Researchers discovered that the neuropsychiatric symptoms in Alzheimer’s disease, such as irritability, agitation, and depression, primarily stem from brain inflammation rather than amyloid and tau proteins. This study involved 109 elderly individuals and found a strong correlation between neuroinflammation and these challenging symptoms.

Featured Neuroscience Psychology

·November 14, 2023·6 min read

Brain Inflammation Linked to Suicide Risk

A new study reveals critical brain changes linked to suicide risk. The research identified overactive inflammation and the loss of protective brain mechanisms as key factors. This breakthrough supports the potential use of anti-inflammatory medications to mitigate suicide risk, particularly in early stages of suicidal ideation.

This shows a child and a glowing brain model.

Autism Featured Neuroscience Psychology

·October 12, 2023·6 min read

Is Inflammation in Childhood A Mechanistic Link to Neurodevelopmental Disorders?

Scientists unveiled a potentially transformative link between early childhood inflammation and the subsequent development of neurodevelopmental disorders, through a pioneering study that utilizes single-cell genomics. By examining brain tissues of children who experienced severe inflammation, they uncovered that such inflammation impedes the full maturation of specific neurons in the cerebellum, a crucial brain region for motor control and cognitive functionality.

Featured Neurology Neuroscience

·September 25, 2023·5 min read

Decoding Brain Inflammation

Researchers studied the TSPO protein, a marker for visualizing cerebral inflammation. Although used in hundreds of PET scans, its exact significance in relation to inflammation remained uncertain.

Featured Neuroscience

·August 8, 2023·5 min read

Wheat Gluten Spurs Brain Inflammation

Researchers found that wheat gluten induces brain inflammation in mice, a finding that could have implications for human health. The study revealed that when mice consumed gluten, inflammation occurred in the hypothalamic region of the brain, which plays a vital role in regulating metabolism.

Featured Neuroscience Open Neuroscience Articles

·March 16, 2023·4 min read

Unlocking the Fountain of Youth: Dietary Supplement Reverses Aging by Countering Menin Loss

Supplementing the amino acid D-serine helped to mitigate some of the age-related changes associated with a decline of the hypothalamic hormone Menin in mouse models.

Featured Neuroscience

·March 6, 2023·5 min read

How Heavy Alcohol Consumption Increases Brain Inflammation

The immune signaling molecule interleukin 1B (IL-1B) is present at higher levels in mouse models of alcohol use disorder. The IL 1B pathway plays a different role in animal models of AUD, causing inflammation in brain areas that play a critical role in decision-making.

Autism Featured Neuroscience

·March 3, 2023·6 min read

Age-Related Brain Differences in Autistic Individuals

Genes linked to inflammation, neurotransmission, and immunity act differently in the brains of those on the autism spectrum compared to neurotypical people. These differences begin during childhood and evolve throughout a person's lifespan.

Featured Neurology Neuroscience

·February 15, 2023·4 min read

Multiple Sclerosis Discovery Could End Disease’s Chronic Inflammation

Blocking the activity of the reactor called the aryl hydrocarbon receptor in T cells resulted in both a decrease in inflammation and recovery in mouse models of multiple sclerosis.

Featured Neuroscience Open Neuroscience Articles

·February 10, 2023·4 min read

Cocaine Use Disorder Alters Gene Networks of Neuroinflammation and Neurotransmission in Humans

Cocaine use disorder alters gene expression in the nucleus accumbens and caudate nucleus, brain areas associated with reward, and the mediation of habit formation.

Featured Neurology Neuroscience Pain

·January 30, 2023·5 min read

Calcium Channels Regulate Neuroinflammation and Neuropathic Pain

The Orai1 class of calcium channels regulates sex differences in the functioning of immune cells associated with neuroinflammation and neuropathic pain.

Featured Neuroscience Psychology

·January 27, 2023·4 min read

A Drug That Increases Dopamine Can Reverse the Effects of Inflammation on the Brain in Depression

Levodopa, a drug commonly prescribed for the treatment of Parkinson's disease that increases dopamine in the brain was found to reverse the effects of neuroinflammation on the reward system and improve symptoms associated with depression.

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