Your sleep history during middle age may predict Alzheimer's pathology later in life. A decrease in sleep quality between 50 and 70 years of age is associated with higher levels of tau and amyloid beta in the brain. Changes in brain activity and quality of sleep could be a biomarker for Alzheimer's disease.
During early Alzheimer's disease, SOD1 initially weakens levels of Tau protein. However, as the disease progresses, the antioxidant becomes less effective at protecting the brain against neurodegeneration.
A new study sheds light on the stabilizing forces of amyloid fibrils associated with Alzheimer's, type 2 diabetes and other neurodegenerative disorders.