Two existing medications show promise in the treatment of the deadly childhood cancer, neuroblastoma. Phenformin and AZD3965 exploit the metabolic hunger of the disease to kill cancer cells without inflicting excessive damage to healthy tissue.
Using computer assisted technology to map cell types and molecular cascades, researchers have discovered potential new treatment strategies for recurrent Sonic Hedgehog Medulloblastoma.
Karolinska Institute researchers report over-expression of the estrogen receptor causes neuroblastoma cells to mature into neuron-like cells.
Based on a large scale meta analysis, researchers report striking differences between children's high grade gliomas, so much so that they could be split into 10 different subtypes based on different characteristics. The findings have important implications for developing new and individualized treatments.
A new study reveals how LMO1 works wih the MYCN gene to fuel the spread of neuroblastoma brain cancer.
