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Multiple Sclerosis

·November 4, 2024·4 min read

Keto Diet May Ease Multiple Sclerosis Symptoms

New research suggests the ketogenic diet could help manage multiple sclerosis (MS) by promoting the production of beneficial compounds in the gut. In a study, mice on a keto diet produced the ketone body β-hydroxybutyrate (βHB), which worked with gut bacteria to create immune-modulating metabolites.

Featured Neuroscience

·November 3, 2024·8 min read

Researchers Create Cell-Level Wearable Devices to Restore Neuron Function

Researchers have developed tiny, wireless devices capable of wrapping around individual neurons, potentially aiding in the treatment of neurological disorders like multiple sclerosis. These devices, made from a soft polymer, roll up snugly around cell structures when exposed to light, allowing precise measurement and modulation of cellular activity. As they’re battery-free and actuated noninvasively by light, thousands of them could be deployed in the body simultaneously.

Featured Neurology Neuroscience

·November 1, 2024·3 min read

High Palm Oil Diet Worsens MS Symptoms by Triggering Neurotoxic Pathway

New research highlights how a palm oil-rich diet may worsen multiple sclerosis (MS) symptoms by generating a toxic compound in neurons. Researchers found that enzymes CerS5 and CerS6 convert palm oil into a substance that damages mitochondria, depriving neurons of essential energy.

Featured Genetics Neurology Neuroscience

·October 21, 2024·5 min read

Viral DNA in Our Genome Linked to ALS and MS Susceptibility

A new study reveals that ancient viral DNA embedded in the human genome is associated with genetic risk for amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS). Researchers found specific human endogenous retroviruses (HERVs) that influence susceptibility to these neurodegenerative diseases.

Featured Neurology Neuroscience

·October 15, 2024·3 min read

AI-Enhanced MRIs Show Potential for Brain Abnormality Detection

Researchers have developed a machine learning model that upgrades 3T MRI images to mimic the higher-resolution 7T MRI, providing enhanced detail for detecting brain abnormalities. The synthetic 7T images reveal finer features, such as white matter lesions and subcortical microbleeds, which are often difficult to see with standard MRI systems. This AI-driven approach could improve diagnostic accuracy for conditions like traumatic brain injury (TBI) and multiple sclerosis (MS), though clinical validation is needed before wider use.

Featured Neurology Neuroscience

·October 2, 2024·4 min read

Personalized Immune Therapy Offers Hope for MS Patients

A new study explores the use of tolerogenic dendritic cells (tolDCs) to restore immune balance in multiple sclerosis (MS) patients without compromising their immune system. The research reveals that MS patients’ immune cells have a pro-inflammatory signature, even after being modified for therapy.

Featured Neurology Neuroscience

·October 1, 2024·4 min read

Early Immune Cell Changes May Predict Multiple Sclerosis Onset

A new study shows that CD8-positive T cells play a significant role in the early stages of multiple sclerosis (MS). By studying identical twins where one twin has MS and the other is asymptomatic, researchers found that CD8 T cells exhibit specific changes before symptoms arise, including increased migration and inflammation promotion.

Featured Neurology Neuroscience

·September 24, 2024·3 min read

Early MS Symptoms Linked to Long-Term Disability Outcomes

Certain initial symptoms of multiple sclerosis (MS), like blurry vision and sphincter dysfunction, may predict long-term disability outcomes. Researchers found that patients experiencing these symptoms at disease onset had a higher risk of severe disability over time.

Featured Genetics Neurology Neuroscience

·August 28, 2024·4 min read

Increase in Protein Linked to Salt Intake Implicated in Multiple Sclerosis

Researchers have uncovered that increased levels of the protein PRDM1-S, triggered by high salt intake, disrupt immune regulation and contribute to autoimmune diseases like multiple sclerosis (MS). This discovery reveals how environmental factors, such as diet, can influence genetic mechanisms, leading to T cell dysfunction. The findings suggest that targeting PRDM1-S could lead to new treatments for a range of autoimmune disorders.

Featured Neurology Neuroscience

·August 23, 2024·5 min read

Does Multiple Sclerosis Lower Dementia Risk?

Research has revealed that individuals with multiple sclerosis (MS) are significantly less likely to exhibit the molecular signs of Alzheimer’s disease, suggesting a protective element in MS that could inspire new Alzheimer's treatments. The study found that MS patients had 50% less amyloid plaque accumulation, a key indicator of Alzheimer’s, compared to non-MS individuals. This connection between MS and reduced Alzheimer's risk highlights potential immune-related mechanisms that may be leveraged for therapeutic strategies.

Featured Neurology Neuroscience

·August 5, 2024·7 min read

New Multiple Sclerosis Drug Regenerates Myelin, Improves Movement

A new drug, PIPE-307, shows promise in reversing multiple sclerosis (MS) damage by promoting myelin regeneration around nerve cells, potentially restoring movement and function. Developed by researchers, this innovative therapy targets a specific receptor, M1R, and has already demonstrated success in animal models. PIPE-307 is currently in Phase II clinical trials, offering hope for a groundbreaking treatment that could stop and even heal the damage caused by MS. This novel approach could transform the future of MS therapy by addressing both symptoms and underlying damage.

Featured Neurology Neuroscience

·June 7, 2024·5 min read

Epstein-Barr Virus Plays Critical Role in Multiple Sclerosis

Epstein-Barr Virus (EBV) may cause multiple sclerosis (MS) through higher levels of immune cross-reactivity than previously thought. Researchers found that T-cells targeting EBV can also recognize brain proteins, a misdirection seen in both MS patients and healthy individuals.

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Multiple Sclerosis

Keto Diet May Ease Multiple Sclerosis Symptoms

Researchers Create Cell-Level Wearable Devices to Restore Neuron Function

High Palm Oil Diet Worsens MS Symptoms by Triggering Neurotoxic Pathway

Viral DNA in Our Genome Linked to ALS and MS Susceptibility

AI-Enhanced MRIs Show Potential for Brain Abnormality Detection

Personalized Immune Therapy Offers Hope for MS Patients

Early Immune Cell Changes May Predict Multiple Sclerosis Onset

Early MS Symptoms Linked to Long-Term Disability Outcomes

Increase in Protein Linked to Salt Intake Implicated in Multiple Sclerosis

Does Multiple Sclerosis Lower Dementia Risk?

New Multiple Sclerosis Drug Regenerates Myelin, Improves Movement

Epstein-Barr Virus Plays Critical Role in Multiple Sclerosis

How Cool Touch Travels From Skin to Brain

What You Expect Shapes How Much Pain You Feel

Women’s Scent During Ovulation Alters Male Stress and Attraction

Irregular Sleep Linked to 172 Diseases

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