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          mitophagy

          This shows a photoreceptor model, AI generated.
          FeaturedGeneticsNeuroscienceVisual Neuroscience
          ·March 11, 2026·8 min read

          Bringing Sight Back: Photoreceptor Cell Death Is Reversible

          Scientists discover that dying eye cells can be rescued by clearing out "toxic batteries," potentially preventing permanent blindness.
          Read More
          This shows a brain.
          FeaturedGeneticsNeuroscience
          ·November 15, 2024·5 min read

          How the Brain’s Recycling Changes with Age

          New research uncovers how mitophagy, the cellular recycling of damaged mitochondria, changes dynamically in the aging mammalian brain. In memory-related cells, mitophagy rises in midlife but declines sharply in old age, while motor-related brain cells show increased mitophagy with age.
          Read More
          This shows a cell with mitochondrial damage
          FeaturedGeneticsNeurologyNeuroscience
          ·May 16, 2019·3 min read

          Miro2 is a Parkin receptor for selective removal of damaged mitochondria

          Findings from a mouse model study reveal Miro2 functions as a platform for Parkin translocation and damaged mitochondrial clearance.
          Read More
          mitochondria
          FeaturedGeneticsNeurology
          ·February 15, 2019·3 min read

          ‘Lack of Cleaning’ in Brain Cells is Central to Alzheimer’s

          Researchers report dysfunctional mitophagy may contribute to the development of Alzheimer's disease. When mitophagy is improved, symptoms of Alzheimer's almost disappeared in animal models of the disease.
          Read More
          This is an illustration of PINK1 removing mitochondria.
          FeaturedGeneticsNeurology
          ·August 12, 2015·3 min read

          New Potential Pathway for Treating ALS and Parkinson’s Diseases

          A new study reports PINK1 triggers mitophagy, a process which breaks down and removes damaged mitochondria from cells.
          Read More

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          A 3D digital rendering showing a developing fetal brain connected by glowing neural pathways and floating DNA strands, surrounded by subtle immune cells.

          How Severe Illness During Pregnancy Alters Fetal Brain Development

          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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