FeaturedGeneticsNeuroscience·November 15, 2024·5 min readHow the Brain’s Recycling Changes with AgeNew research uncovers how mitophagy, the cellular recycling of damaged mitochondria, changes dynamically in the aging mammalian brain. In memory-related cells, mitophagy rises in midlife but declines sharply in old age, while motor-related brain cells show increased mitophagy with age.Read More
FeaturedGeneticsNeurologyNeuroscience·May 16, 2019·3 min readMiro2 is a Parkin receptor for selective removal of damaged mitochondriaFindings from a mouse model study reveal Miro2 functions as a platform for Parkin translocation and damaged mitochondrial clearance.Read More
FeaturedGeneticsNeurology·February 15, 2019·3 min read‘Lack of Cleaning’ in Brain Cells is Central to Alzheimer’sResearchers report dysfunctional mitophagy may contribute to the development of Alzheimer's disease. When mitophagy is improved, symptoms of Alzheimer's almost disappeared in animal models of the disease.Read More
FeaturedGeneticsNeurology·August 12, 2015·3 min readNew Potential Pathway for Treating ALS and Parkinson’s DiseasesA new study reports PINK1 triggers mitophagy, a process which breaks down and removes damaged mitochondria from cells.Read More
