In mice, the failed epigenetic suppression of Xist leads to fetal developmental abnormalities and miscarriage. Knocking out the Xist gene greatly reduced prenatal death. The findings have implications for understanding infertility and developing new treatments to prevent miscarriage.
Women who experience unexplained repeated pregnancy loss (uRPL) process olfactory signals related to male body odor differently to other women. Those who experience uRPL are better able to identify the smell of their spouse.
Ectopic pregnancy and early miscarriage can trigger lasting PTSD in one in six women. A month after pregnancy loss, 29% of women reported PTSD symptoms. 24% of women suffered moderate to severe anxiety, and 11% of women reported moderate to severe depression. Following up after nine months, 18% reported continuing PTSD symptoms, 17% reported severe anxiety, and 6% of women said they still experienced severe depression as a result of the loss of pregnancy.
Women who experience migraines while pregnant are at increased risk of miscarriage, caesarean sections, preterm labor and delivering babies with low birth weight.
Women with autoimmune disease neuromyelitis optica are at increased risk of miscarriage and preeclampsia during pregnancy, a new study reports.