FeaturedNeurologyNeuroscience·March 25, 2020An aspirin a day does not keep dementia at bayContrary to popular belief, taking a low-dose of aspirin daily does not reduce the risk of developing mild cognitive impairment (MCI). Researchers found no difference between older people who took aspirin and those who took a placebo in the risk of developing MCI, dementia, or Alzheimer's disease. Read More
FeaturedNeurologyNeuroscience·January 1, 2020Objective subtle cognitive difficulties predict amyloid accumulation and neurodegenerationAmyloid accumulation occurs faster in those who have objectively-defined cognitive difficulties than older people who are considered to be cognitively normal. Mild cognitive impairment is also associated with faster hippocampal and entorhinal cortex atrophy. Read More
FeaturedNeurologyNeuroscience·December 30, 2019What comes first, beta-amyloid plaques or thinking and memory problems?Subtle changes in thinking and memory may appear before, or in conjunction with, the development of amyloid plaques. Read More
FeaturedNeurologyNeuroscience·December 29, 2019Drugs that quell brain inflammation reverse dementiaOlder mice given anti-inflammatory medication were better able to learn new tasks and became almost as adept at learning as mice half their age. Read More
FeaturedNeurologyNeuroscience·December 4, 2019Drugs that quell brain inflammation reverse dementiaA synthesized small-molecule drug blocks the TGF-beta receptor in astrocytes and traverses the blood-brain barrier in mice. When administered, the drug lowered receptor activity to that seen in younger mice and reduced inflammation. The aged mice were able to navigate mazes and learn spatial tasks as well as younger mice. Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·November 29, 2019Aerobic exercise and heart-healthy diet may slow development of memory problemsCombining aerobic exercise with the heart-healthy DASH diet improved the ability to think, recall, and make decisions in older people who experienced cognitive decline and mild cognitive impairment. Read More
FeaturedNeurologyNeuroscience·October 28, 2019Looking at the way we walk can help predict cognitive declineGait disorders and slowed walking speeds may be useful indicators of future cognitive decline. Read More
FeaturedNeurologyNeuroscience·September 17, 2019Exercise could slow withering effects of Alzheimer’sFor those with mild cognitive impairment (MCI) and other risk factors for Alzheimer's disease, participating in aerobic exercise several times a week may slow neurodegeneration. Aerobic exercise reduced hippocampal atrophy in those with MCI. Read More
FeaturedGeneticsNeurologyNeuroscience·September 15, 2019How the eyes might be windows to the risk of Alzheimer’s diseaseAdults with mild cognitive impairment (MCI), a precursor to Alzheimer's disease, have greater pupil dilation when taking cognitive tests than their cognitively normal peers. Task-evoked pupillary response may be a cost-effective, and low invasive screening test for those at genetic risk for Alzheimer's before the symptoms of the disease take hold. Read More
FeaturedNeurologyNeuroscience·August 16, 2019Adults with mild cognitive impairment can learn and benefit from mindfulness meditationOlder adults with mild cognitive impairment who practiced mindful meditation for 20 minutes a day were more likely to have an understanding of the underlying concepts of mindfulness. The study demonstrates memory impairments associated with MCI do not preclude learning mindfulness skills. Read More
FeaturedNeurologyNeuroscience·July 10, 2019Can computer use, crafts and games slow or prevent age-related memory loss?Middle-aged and older people who stay mentally active have a lower risk of developing mild cognitive impairment. Read More
FeaturedNeurologyNeuroscience·June 28, 2019Pink noise boosts deep sleep in mild cognitive impairment patientsShort pulses of pink noise played during slow-wave sleep can help improve memory consolidation for those with mild cognitive impairment. Read More
