Study reports success in treating cognitive decline and memory loss associated with Alzheimer's disease with the aid of personalized precision medicine. Read More
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22% of study participants with severe gum disease developed dementia, and 23% diagnosed with mild cognitive impairment suffered extreme tooth loss. Only 14% of those with healthy gums were later diagnosed with the neurodegenerative disorder. The findings add further evidence for the link between dental hygiene and dementia. Read More
Certain personality traits could increase the risk of developing mild cognitive impairment, a new study reports. Openness was associated with a 6% reduced risk of developing a pre-dementia condition, while those who scored higher for neuroticism had a 6% increased risk of MCI. Read More
Contrary to popular belief, taking a low-dose of aspirin daily does not reduce the risk of developing mild cognitive impairment (MCI). Researchers found no difference between older people who took aspirin and those who took a placebo in the risk of developing MCI, dementia, or Alzheimer's disease. Read More
Amyloid accumulation occurs faster in those who have objectively-defined cognitive difficulties than older people who are considered to be cognitively normal. Mild cognitive impairment is also associated with faster hippocampal and entorhinal cortex atrophy. Read More
Subtle changes in thinking and memory may appear before, or in conjunction with, the development of amyloid plaques. Read More
Older mice given anti-inflammatory medication were better able to learn new tasks and became almost as adept at learning as mice half their age. Read More
A synthesized small-molecule drug blocks the TGF-beta receptor in astrocytes and traverses the blood-brain barrier in mice. When administered, the drug lowered receptor activity to that seen in younger mice and reduced inflammation. The aged mice were able to navigate mazes and learn spatial tasks as well as younger mice. Read More
Combining aerobic exercise with the heart-healthy DASH diet improved the ability to think, recall, and make decisions in older people who experienced cognitive decline and mild cognitive impairment. Read More
Gait disorders and slowed walking speeds may be useful indicators of future cognitive decline. Read More
For those with mild cognitive impairment (MCI) and other risk factors for Alzheimer's disease, participating in aerobic exercise several times a week may slow neurodegeneration. Aerobic exercise reduced hippocampal atrophy in those with MCI. Read More
Adults with mild cognitive impairment (MCI), a precursor to Alzheimer's disease, have greater pupil dilation when taking cognitive tests than their cognitively normal peers. Task-evoked pupillary response may be a cost-effective, and low invasive screening test for those at genetic risk for Alzheimer's before the symptoms of the disease take hold. Read More
