Researchers have uncovered a neural mechanism in female mice that shifts estrogen from playing a protective role in glucose metabolism to a disruptive one.
A new mouse study reveals a drug compound is effective at treating and potentially reversing symptoms of Fragile x syndrome.
PET imaging study reveals higher levels of mGluR5 in those with PTSD who had suicidal thoughts. The findings could serve as a biomarker to assess suicide risk in people with PTSD.
Researchers report specific alterations in signaling circuits associated with memory can induce an abnormal response in neurons, which is linked to the aging process and cognitive decline.
Researchers have successfully reduced some symptoms associated with fragile X syndrome in mice with the help of CRISPR-Cas 9 gene editing.
Using CRISPR gene editing technology, researchers target the Shank3 gene in monkey embryos. Research backs previous findings of the importance of the Shank3 gene for brain development and its role in autism.
A recent study in PNAS implicates alterations in the brain's glutamate signaling in people with PTSD. Neuroimaging revealed increased levels of mGluR5 in those with post traumatic stress disorder. Researchers report drugs that can reduce mGluR5 function could help reduce fear, stress and other symptoms of PTSD.
A new drug has proven effective at restoring memories and neural connections in mouse models of Alzheimer's disease. The new drug was originally developed as a treatment for Schizophrenia. While the drug does not destroy amyloid plaques associated with Alzheimer's, it does allow the plaques to co-exist with neurons.
A new study looks at some of the underlying causes of fragile X syndrome and offers suggestions for new treatment targets.
A new study provides a deeper understanding of the mechanisms behind OCD and suggests the disorder could be treated by a class of drugs that has been investigated in clinical trails.
A new imaging technique could help to provide a way to break the cycle of alcoholism.
Researchers have developed a new mouse model of a genetically linked type of autism. The new model helps reveal more about the role of genes and brain changes associated with the disorder.
