HDAC5, the "epigenetics" enzyme, plays a key role in limiting opioid-associated memories and drug-seeking behaviors following abstinence from drugs in rats. The findings provide a new avenue for the treatment of opioid addiction.
The direct phosphorylation of KCNQ2 by ERK occurs through the activation of the dopamine signaling pathway in the nucleus accumbens of mice.
Inducing massive inflammation resulted in an overexpression of Trpv4. The overexpression led to neural hyperexcitability that resulted in social avoidance behaviors associated with ASD in mouse models.
According to a new study, nicotine reduces dorsal striatal output, underlying the urge to smoke and making it difficult to quite the addiction.
Targeting a protein associated with addiction could help reduce aggression levels, researchers report.
Researchers have identified different neuron types and provided a new list of genes associated with schizophrenia. The findings could pave the way for developing new targeted therapies to treat the condition.
Vanderbilt researchers have mapped a signaling system in the brain that appears to be linked to autism.
Researchers reveal the role PRC2 plays in Huntington's disease and other neurodegenerative diseases.
According to a new study, alcohol consumption alters the function of medium spiny neurons in the dorsomedial striatum.
