HDAC5, the "epigenetics" enzyme, plays a key role in limiting opioid-associated memories and drug-seeking behaviors following abstinence from drugs in rats. The findings provide a new avenue for the treatment of opioid addiction.
A newly discovered neural circuit in the thalamus prevented reward-seeking behaviors when activated in a preclinical model. When blocked, this circuit increases high-risk reward-seeking behaviors. The findings could lead to new therapies for addiction and other disorders associated with high-risk reward-seeking behaviors.
A new study seeks to better understand how cannabis use alters the oral microbiome and how this may have an impact on neurodegenerative disorders.
MEF2C, a gene critical for brain development and regulating circuit formation in the brain also plays a significant role in inner ear development. Mutations of MEF2C have previously been linked to ASD. Researchers found mice with only one copy of the MEF2C gene had reduced activity in the auditory nerve.
People who experienced sexual abuse or suffer from PTSD have reduced connectivity in the ventral and dorsal attention network (VAN-DAN network) compared to those with no history of abuse or PTSD.
Bach1, a protein that blocks the expression of genes associated with neuroprotection, has been implicated in Parkison's disease. Researchers say blocking Bach1 slows the deterioration of brain cells in preclinical models of Parkinson's disease.
Mouse study reveals females with the EPHB2 genetic mutation are at greater risk of autism.
Using artificial intelligence and neuroimaging, researchers have identified a link between mental imagery and vision. The brain uses similar visual areas for mental imagery and vision but uses low-level visual areas less precisely for mental imagery than vision.
Study contradicts the conventional belief that burnout is associated with workplace factors, and depressive symptoms are more heavily influenced by personal factors. Burnout, researchers say, is much more closely related to factors that drive depression than previously thought.
A new neuroimaging study reveals pericytes, a type of cell found in the brain's blood vessels, grow to compensate for the loss of neighboring cells.
A new study reports misfolded proteins can cause circadian rhythm disruptions which contribute to cancerous tumor growth.
Researchers report a blink reflexometer may help doctors to diagnose neurological problems, from TBI to Parkinson's disease, in patients.
