The MeCP2 gene influences ketamine's behavioral effect and strengthens synapses, leading to an improvement in the drug's antidepressant effect over time.
Findings about the distribution of condensates in Rett syndrome shed light on how cells compartmentalize chromosomes and provide new insights into potential paths of therapies for the neurodevelopmental disorder.
Abnormal activation of parvalbumin neurons in the young mouse auditory cortex manifests as a result of maternal neglect.
Isoguavacine, an old experimental compound which exclusively targets peripheral neurons, mitigates abnormal touch sensitivity in mouse models of ASD. The compound also improved body mass, reduces anxiety, and in one genetic subset of mice, prevented the development of brain abnormalities that arise from altered touch response.
Exosomes carry signaling information required to regulate neural circuit development.
Activating neurons in the medial prefrontal cortex can reverse breathing and memory abnormalities in mouse models of Rett syndrome, researchers report.
Mass General researchers have developed a strategy for treating disorders related to the X chromosome.
Researchers have discovered the mechanism behind the fainting disorder, Postural Orthostatic Tachycardia Syndrome.
A new study reports a protein associated with Rett syndrome is also among a group of three proteins that affect the function of a gene previously linked to OCD.
According to new research, one protein can regulate the expression of a large number of genes that modulate pain.
A new study reports some aspects of autism spectrum disorders are linked to defects in how peripheral nerves communicate sensory information to the brain.
Researchers have identified an important signaling pathway that, when corrected, appears to improve symptoms of Rett syndrome in mice.
