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maternal inflammation

·April 1, 2025·4 min read

Maternal Inflammation May Disrupt Infant Brain Wiring

A new study reveals that inflammation during pregnancy may impair neurodevelopment in infants by reducing CD11c-positive microglia—key immune cells that support brain myelination. These cells produce IGF-1, a protein critical for forming the myelin sheath that helps nerve signals travel efficiently.

Featured Genetics Neurology Neuroscience

·November 21, 2024·5 min read

Maternal Inflammation May Shape Offspring’s Alzheimer’s Risk

Maternal immune activity during pregnancy influences memory circuitry in offspring, with sex-specific effects extending into midlife. Elevated immune markers like IL-6 and TNF-a in mothers were linked to adverse brain activity in memory regions, particularly in postmenopausal women, and lower cognitive performance in children.

Featured Neuroscience Psychology

·December 7, 2023·4 min read

Maternal Inflammation Linked to Child Behavioral Dysregulation

Maternal inflammation risk factors may be associated with dysregulation in children, encompassing attention, anxiety, depression, and aggression. Researchers observed that children born to mothers with prenatal infections, or who were overweight, less educated, or smoked during pregnancy, had a higher likelihood of dysregulation.

Featured Neuroscience

·June 22, 2023·4 min read

Inflammation in Womb Disturbs Neuron Maturation, Affects Brain Development

Researchers discovered how inflammation in the womb can disrupt the maturation of nerve cells and impede an unborn baby's brain development. The study reveals that excessive inflammation can lead to reduced neuronal electrical activity, possibly resulting in conditions like cerebral palsy or developmental issues affecting growth, movement, vision, and hearing.

Autism Featured Neuroscience Psychology

·May 4, 2020·5 min read

New insight on maternal infections and neurodevelopmental disorders

Maternal inflammation has been linked to a range of neurodevelopmental and psychiatric disorders in children, including autism and schizophrenia. A new mouse study reveals maternal responses and subsequent developmental disorders are based on the mother's immunoreactivity to infection.

Featured Neuroscience Open Neuroscience Articles Psychology

·October 30, 2019·3 min read

How are psychiatric disorders linked to infections during pregnancy?

Previous studies have documented how infection during pregnancy can increase the risk of ASD and a range of psychiatric disorders in the offspring. A new study reveals how maternal infections can affect neural development and how the timing of infection plays a critical role in elevating the risks of mental health conditions.

Featured Neuroscience Open Neuroscience Articles

·March 14, 2019·4 min read

Expectant mothers can prevent fetal brain problems caused by the flu

Choline, an essential nutrient, can help prevent fetal brain development problems in infants whose mothers experience common infections, such as influenza, during pregnancy.