Cold Water Swimming May Ease Depression
A new case study reports swimming in cold, open water may help those with major depressive disorder to gain control of their symptoms and possibly live medication free.... Read More...
major depressive disorder
Ketamine’s Antidepressant Effects Tied to Opioid System in the Brain
Researchers report ketamine's antidepressive effects require activation of opioid receptors in the brain. The study highlights the interaction between depression, pain and opioid addiction. ... Read More...
Machine Learning Could Predict Medication Responses in Patients with Complex Mood Disorders
Researchers have developed a new machine learning algorithm which is 94% accurate in predicting which patients with complex mood disorders will respond to medications.... Read More...
Lack of a Single Molecule May Indicate Severe and Treatment Resistant Depression
A new study reports patients with major depressive disorder and treatment resistant depression have decreased levels of acetyl-L-carnitine in their blood. The findings could lead to new blood tests to diagnose the nature and severity of depression.... Read More...
Psychiatric Disorders Share an Underlying Genetic Basis
Researchers have identified genetic overlaps between different types of psychiatric disorders including ADHD, bipolar disorder, MDD and schizophrenia. They also identified an overlap between anorexia and OCD, as well as between Tourettes and OCD.... Read More...
Protein’s Role in Mediating Brain’s Response to Stress Identified
Researchers have identified the role Klf9 plays in the brain's response to stress. The study reports elevated levels of the protein were discovered in the hippocampus of women with MDD who faced stressful events.... Read More...
Virtual Brain Gives Insights Into Memory Deficits in Depression
Researchers have developed a new computational model of major depressive disorder. The model reveals older memories, as well as short term memories, are affected by major depressive disorder. Researchers say how long the memory deficits go back depends on how long the depressive episode lasts.... Read More...
Brain Structure Linked with Sex Based Differences in Anxiety Behavior: Mouse Study
A new mouse study reveals females have a three fold higher abundance of EP3, in addition to elevated levels of genes associated with major depressive disorder in the locus coeruleus. ... Read More...
Surprising Finding About ‘Shock Therapy’ for Depression Suggests More Patients Should Try It Sooner
For those with treatment resistant depression, a new study reports ECT may not only be the most effective treatment, but also the most cost effective.... Read More...
Brain Stimulation Reduces Suicidal Thinking in People with Hard to Treat Depression
According to researchers, 40% of people with treatment resistant depression who received rTMS no longer had suicidal thoughts following treatment. ... Read More...
Three Minute Version of Brain Stimulation Therapy Effective for Hard to Treat Depression
Researchers report intermittent theta burst stimulation can help to alleviate the symptoms of major depressive disorder. 49% of patients who received the treatment reported a significant decrease in symptoms, with 32% reporting remission of depression.... Read More...
44 Genetic Risk Factors for Major Depression Identified
Researchers have identified 44 genetic risk factors for major depressive disorder. 30 of the variants are newly discovered. The team reports the genetic basis for MDD is shared with other psychological disorders and all humans carry some of the genetic risk factors identified.... Read More...