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major depressive disorder

This shows a depressed looking woman looking out a window with a coffee in her hand

·March 16, 2022·5 min read

Spending More Time at Home Is Linked to More Severe Symptoms in People With Depression

People with major depressive disorder who spent more time at home during a two-week period reported more severe symptoms of depression.

This shows a man with a bottle looking over the edge of a bridge

Featured Neuroscience Psychology

·March 9, 2022·5 min read

Alcohol Dependence Significantly Increases Suicide Risk

Alcohol use disorder is associated with a significant increase in suicidal thoughts in adults.

Featured Neuroscience Psychology

·February 15, 2022·6 min read

Psilocybin Treatment for Major Depression Effective for up to a Year for Most Patients

The antidepressant effect of psilocybin-assisted therapy, in combination with psychotherapy, appears to provide up to a year of symptom relief for some patients with major depressive disorder.

Featured Neuroscience Psychology

·January 28, 2022·4 min read

Patients With Schizophrenia, Major Depression and Bipolar Disorder Have Distinct Reward Neural Mechanisms

While patients with schizophrenia, major depressive disorder, and bipolar disorder experience a lack of motivation and anhedonia, the neural patterns of emotion-behavior dissociation differ between the disorders.

Featured Neuroscience Open Neuroscience Articles Psychology

·January 11, 2022·3 min read

Why Severe Depression Affects Women and Men Differently

Researchers found alterations in different parts of the brain in males and females with severe depression. The findings also reveal a specific biomarker for depression in blood samples of women.

This is a cartoon of a head and a man standing behind, pulling out string from the brain

Featured Neuroscience Open Neuroscience Articles Psychology

·December 5, 2021·4 min read

New Insight Into How Antidepressant Drugs Work

Hippocampal HCN channels are more highly expressed in people with major depressive disorder. Antidepressants that increase cAMP signaling interfere with TRIP8b's ability to bind to HCN channels, helping to restore cognitive ability in those with MDD.

Featured Neuroscience Open Neuroscience Articles Psychology

·July 30, 2021·3 min read

Olfactory Sensitivity Show Postpartum Depression is Different to Major Depression

Women with postpartum depression report normal olfactory sensitivity, while those who are genetically predisposed to major depressive disorder have decreased olfactory sensitivity.

Featured Neuroscience Psychology

·July 28, 2021·6 min read

Improved Learning Processes Tied to Reduced Symptoms of Depression

Specific neural learning processes are linked to symptoms of depression. Improvements in the learning processes were associated with overall improvements in depression symptoms.

Featured Psychology

·June 9, 2021·4 min read

Low Doses of “Laughing Gas” Could Be Fast, Effective Treatment for Severe Depression

Nitrous oxide, a common anesthesia most often associated with dental procedures, may have a new purpose. Researchers found a single inhalation of 25% nitrous oxide gas was effective at alleviating symptoms of depression in those with a treatment-resistant form of the mental health disorder.

This shows a sad looking woman standing at a window

Featured Genetics Neuroscience Psychology

·May 27, 2021·4 min read

Roots of Major Depression Revealed in All Its Genetic Complexity

A new, massive genome wide study has identified 178 genetic variants linked to major depressive disorder.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·April 6, 2021·6 min read

Accelerated Cellular Aging Associated With Mortality Seen in Depressed Individuals

DNA markers in cells of patients with major depressive disorder appear to be two years older than markers in cells of people without the mental health disorder.

Featured Genetics Neuroscience Psychology

·March 23, 2021·5 min read

Large-Scale Genome Analysis Identifies Differences by Sex in Major Psychiatric Disorders

Researchers found that while there are genetic overlaps between the sexes in relation to mental health disorders, there are also sex-specific differences in how genes related to the immune system, central nervous system, and blood vessels affect people with mental health problems.

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major depressive disorder

Spending More Time at Home Is Linked to More Severe Symptoms in People With Depression

Alcohol Dependence Significantly Increases Suicide Risk

Psilocybin Treatment for Major Depression Effective for up to a Year for Most Patients

Patients With Schizophrenia, Major Depression and Bipolar Disorder Have Distinct Reward Neural Mechanisms

Why Severe Depression Affects Women and Men Differently

New Insight Into How Antidepressant Drugs Work

Olfactory Sensitivity Show Postpartum Depression is Different to Major Depression

Improved Learning Processes Tied to Reduced Symptoms of Depression

Low Doses of “Laughing Gas” Could Be Fast, Effective Treatment for Severe Depression

Roots of Major Depression Revealed in All Its Genetic Complexity

Accelerated Cellular Aging Associated With Mortality Seen in Depressed Individuals

Large-Scale Genome Analysis Identifies Differences by Sex in Major Psychiatric Disorders

Can AI Assistants Like ChatGPT Help Address Public Health Questions?

Colorful Foods for Enhanced Visual Range

Emotional Switchboard in Mouse Brain Reveals Infanticide Trigger

Alzheimer’s Plaques Might Contribute to Hearing Loss

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