LRRK2 Research Articles - Neuroscience News

New method developed to target cause of Parkinson’s

Neuroscience NewsMay 3, 2019

Clioquinol, an anti-parasitic medication, overcomes the effect of mutations in the LRRK2 gene associated with Parkinson's disease by restoring the acidity of lysosomes and clearing out protein aggregates. ... Read More...

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This shows the chemical structure of vitamin b12

Vitamin B12 identified as the inhibitor of a key enzyme in hereditary Parkinson’s disease

Neuroscience NewsApril 4, 2019

Vitamin B12 significantly prevents the neurotoxicity of LRRK2 genetic variants associated with hereditary Parkinson's disease. The findings may help with the development of new therapies to combat the neurodegenerative disease. ... Read More...

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Defective Glial Cells Can Push Neurons Toward Parkinson’s Disease

Neuroscience NewsJanuary 10, 2019

A new study reveals a defective version of astrocytes may be linked to the build up of alpha synuclein and could spur Parkinson's disease. The findings show the important role glial cells play in Parkinson's and offers insights into new targets for therapies to fight the neurodegenerative disease.... Read More...

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Early Synaptic Dysfunction Found in Parkinson’s Disease

Neuroscience NewsMay 24, 2018

Mutations in LRRK2 leads to dysfunctional auxilin and impaired synaptic vesicle endocytosis in Parkinson's patients, researchers report.... Read More...

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Link Between Tuberculosis and Parkinson’s Disease Discovered

Neuroscience NewsMay 22, 2018

Studying what the LRRK2 gene does in macrophages infected with the bacterium that causes tuberculosis, researchers believe they may have identified a cause of Parkinson's disease.... Read More...

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Parkinson’s Gene Initiates Disease Outside of the Brain

Neuroscience NewsMarch 21, 2018

A new study reveals the LRRK2 genetic mutation may alter cells circulating outside of the brain. Researchers report the mutation may alter how immune cells react to common illnesses, causing an inflammatory reaction in the brain that can lead to the development of Parkinson's disease.... Read More...

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Parkinson’s Gene Needed For Dopamine Neuron Health

Neuroscience NewsOctober 26, 2017

A new study reveals LRRK is essential for the survival of dopamine neurons in the brain. The finding may prompt new treatments for Parkinson's disease.... Read More...

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Single Protein May Hold Secret to Treating Parkinson’s

Neuroscience NewsDecember 26, 2016

Activating Nrf2 helps with the removal of LRRK2 and alpha synuclein, researchers report.... Read More...

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Image shows the structure of the LRRK2 protein.

Researchers Uncover a New Disruption at the Root of Parkinson’s

Neuroscience NewsOctober 9, 2016

Researchers have discovered a genetic mutation that causes Parkinson's can prevent synapses from coping with the stress of intense brain activity.... Read More...

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Discovery May Lead to a Treatment to Slow Parkinson’s

Neuroscience NewsJuly 19, 2016

Researchers have discovered an interaction in neurons that contributes to Parkinson's disease.... Read More...

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Parkinson’s Biomarker Found in Patient Urine Samples

Neuroscience NewsJuly 5, 2016

Researchers have discovered a new type of biomarker for Parkinson's in stored urine and cerebral spinal fluid samples of people with the disease.... Read More...

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New Gene Shown to Cause Parkinson’s Disease

Neuroscience NewsJune 6, 2016

Researchers have identified that mutations in the TMEM230 gene may be a cause of Parkinson's disease.... Read More...

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News

Pregnant women increase peripersonal space to ‘keep dangers at arm’s length’

Many choices seems promising until you actually have to choose

Artificial nose identifies malignant tissue in brain tumors during surgery

Neuroscience

Pregnant women increase peripersonal space to ‘keep dangers at arm’s length’

Many choices seems promising until you actually have to choose

Artificial nose identifies malignant tissue in brain tumors during surgery

Neurology

Artificial nose identifies malignant tissue in brain tumors during surgery

Modified protein can prevent Alzheimer’s disease in mice

Moral emotions, a diagnostic tool for frontotemporal dementia?

AI

The whisper of schizophrenia: Machine learning finds ‘sound’ words predict psychosis

AI used to detect brain’s response to multiple sclerosis treatment

Brain activation provides individual-level prediction of bipolar disorder risk

Robotics

Research moves closer to brain-machine interface autonomy

Six fingers per hand: Polydactyly equals extra motor ability

Dog-like robot made by students jumps, flips and trots

Psychology

Pregnant women increase peripersonal space to ‘keep dangers at arm’s length’

Many choices seems promising until you actually have to choose

Moral emotions, a diagnostic tool for frontotemporal dementia?

LRRK2

New method developed to target cause of Parkinson’s

Vitamin B12 identified as the inhibitor of a key enzyme in hereditary Parkinson’s disease

Defective Glial Cells Can Push Neurons Toward Parkinson’s Disease

Early Synaptic Dysfunction Found in Parkinson’s Disease

Link Between Tuberculosis and Parkinson’s Disease Discovered

Parkinson’s Gene Initiates Disease Outside of the Brain

Parkinson’s Gene Needed For Dopamine Neuron Health

Single Protein May Hold Secret to Treating Parkinson’s

Researchers Uncover a New Disruption at the Root of Parkinson’s

Discovery May Lead to a Treatment to Slow Parkinson’s

Parkinson’s Biomarker Found in Patient Urine Samples

New Gene Shown to Cause Parkinson’s Disease