A new study reveals a defective version of astrocytes may be linked to the build up of alpha synuclein and could spur Parkinson's disease. The findings show the important role glial cells play in Parkinson's and offers insights into new targets for therapies to fight the neurodegenerative disease.
Researchers have discovered an interaction in neurons that contributes to Parkinson's disease.
Mutations in LRRK2 leads to dysfunctional auxilin and impaired synaptic vesicle endocytosis in Parkinson's patients, researchers report.
Researchers provide new evidence of how to target and reverse the effects caused by the most common genetic mutations for Parkinson's.
Researchers examine mutations of the LRRK2 gene and R1441G, known as the Basque mutation, to better understand Parkinson's disease among patients in the Basque Country.
Studying neurons derived from brain and skin cells of Parkinson's patients, researchers discover how the most common genetic mutations in familial Parkinson's disease damage brain cells.
Studying what the LRRK2 gene does in macrophages infected with the bacterium that causes tuberculosis, researchers believe they may have identified a cause of Parkinson's disease.
A new study reports that a drug currently being used to treat liver disease has shows promise as an effective treatment to slow the progression of Parkinson's disease.
Using stem cells derived from Parkinson's patients, researchers confirm mitochondrial changes.
Clioquinol, an anti-parasitic medication, overcomes the effect of mutations in the LRRK2 gene associated with Parkinson's disease by restoring the acidity of lysosomes and clearing out protein aggregates.