Turning off kappa opioid receptors in the brain decreases the urge the binge drink. Findings suggest the kappa opioid receptor system is important not only for the negative state of withdrawal but also for driving binge drinking behaviors.
A new compound known as BU10119 blocks kappa opioid receptors, creating an antidepressant effect in mice, researchers say.
Opioid receptors involved in itch relief, a new study reports.
A new neuroimaging study links kappa opioid receptors in the brain to a narrow cluster of symptoms associated with PTSD.
Researchers describe a pair of drug candidates which advance the search for new treatments for addiction, pain and other disorders.
A new study provides evidence that the central amygdala, an area of the brain associated with emotion, plays a major role in sustaining cocaine addiction.