Latest

inflammation

Featured Genetics Neurology Neuroscience

·September 30, 2024·5 min read

Genetic Variants Linked to Alzheimer’s Trigger Inflammation in Females

Researchers have discovered that two genetic variants, APOE4 and TREM2 R47H, together cause a harmful inflammatory response in brain immune cells, particularly in females. This response leads to more severe brain damage, including tau protein clumps, which are linked to Alzheimer’s disease progression.

Featured Genetics Neurology Neuroscience

·August 28, 2024·4 min read

Increase in Protein Linked to Salt Intake Implicated in Multiple Sclerosis

Researchers have uncovered that increased levels of the protein PRDM1-S, triggered by high salt intake, disrupt immune regulation and contribute to autoimmune diseases like multiple sclerosis (MS). This discovery reveals how environmental factors, such as diet, can influence genetic mechanisms, leading to T cell dysfunction. The findings suggest that targeting PRDM1-S could lead to new treatments for a range of autoimmune disorders.

Featured Neuroscience Psychology

·August 21, 2024·5 min read

Childhood Inflammation Linked to Later Mental Health Risks

Children with persistent inflammation are at a higher risk of developing mental health disorders like psychosis and depression in early adulthood. A study found that elevated inflammation markers, particularly around age 9, significantly increase the risk of these disorders, as well as cardiometabolic diseases such as insulin resistance. The research suggests that early-life inflammation could be a critical factor in later mental and physical health issues, prompting the need for further investigation into its role.

Featured Genetics Neuroscience

·July 17, 2024·6 min read

Blocking Inflammation Protein Extends Lifespan

Researchers discovered that inhibiting the protein IL-11 extends the lifespan of mice by up to 25%. The treatment also reduces cancer and diseases related to aging.

Featured Neurology Neuroscience

·July 12, 2024·6 min read

Infection Brain Inflammation Triggers Muscle Weakness

A new study reveals how brain inflammation from infections and neurodegenerative diseases causes muscle weakness by releasing the IL-6 protein. Researchers found that IL-6 travels from the brain to muscles, reducing their energy production and function. This discovery could lead to treatments for muscle wasting in diseases like Alzheimer's and long COVID. Blocking the IL-6 pathway may prevent muscle weakness associated with brain inflammation.

Featured Neurology Neuroscience

·July 5, 2024·5 min read

Early Inflammation Linked to Midlife Cognitive Decline

A new study finds that higher inflammation in young adulthood is associated with reduced cognitive function in midlife. Researchers discovered that inflammation due to factors like obesity and smoking can impact memory and processing speed.

Featured Neuroscience

·June 10, 2024·4 min read

Placental Cells Indicate Fetal Brain Health

Fetal placental macrophages can serve as indicators of fetal brain microglia health, which are crucial for brain development. Immune activation in pregnant women, such as from infections or obesity, can negatively affect fetal brain development. The study used mouse models and found that male fetuses are more affected by maternal obesity than females. This research opens avenues for early identification and intervention in neurodevelopmental disorders.

Featured Neuroscience

·June 3, 2024·2 min read

Aspirin Eases Inflammation from Sleep Loss

Low-dose aspirin reduces inflammatory responses caused by sleep restriction. Compared to a placebo, aspirin lowered interleukin-6, COX-1/COX-2 cells, and C-reactive protein levels.

Featured Neurology Neuroscience

·May 2, 2024·6 min read

The Brain’s Role in Immune Control

Researchers discovered that the brain can significantly influence the immune system, particularly its inflammatory responses. The study utilized mice to show that the brain can detect and adjust levels of inflammation via a specific brain circuit involving the caudal nucleus of the solitary tract.

Featured Neuroscience Psychology

·April 26, 2024·4 min read

Maternal Cytokine Levels Linked to Child’s Mental Health

Researchers discovered a critical role for the cytokine XCL1 in fetal brain development and the emotional behavior of offspring, challenging previous assumptions about its low impact due to minimal circulating levels during pregnancy. The study shows that a temporary spike in maternal XCL1 is essential for proper placental development and regulating fear behavior in male offspring.

This shows a woman walking in the woods.

Featured Neurology Neuroscience

·April 22, 2024·3 min read

Outdoor Enjoyment Linked to Less Inflammation

A new study reveals a biological link between enjoying nature and reduced inflammation levels, which could help in preventing or managing chronic inflammation-related diseases like heart disease and diabetes. The study analyzed data from the Midlife in the U.S. (MIDUS) survey, focusing on 1,244 participants, and found that frequent positive interactions with nature correlated with lower levels of three key inflammation markers.

This shows a model of a heart on cracked flooring.

Featured Genetics Neuroscience Psychology

·April 9, 2024·4 min read

Link Between Heart Disease, Depression, and Inflammation Found

A new study uncovered a genetic connection between coronary artery disease, major depression, and an increased risk for cardiomyopathy, mediated through inflammatory pathways. The study highlights that medications used for treating coronary artery disease and depression could synergistically reduce inflammation, potentially preventing cardiomyopathy.

1 … 3 4 5 6 7 … 76

inflammation

Genetic Variants Linked to Alzheimer’s Trigger Inflammation in Females

Increase in Protein Linked to Salt Intake Implicated in Multiple Sclerosis

Childhood Inflammation Linked to Later Mental Health Risks

Blocking Inflammation Protein Extends Lifespan

Infection Brain Inflammation Triggers Muscle Weakness

Early Inflammation Linked to Midlife Cognitive Decline

Placental Cells Indicate Fetal Brain Health

Aspirin Eases Inflammation from Sleep Loss

The Brain’s Role in Immune Control

Maternal Cytokine Levels Linked to Child’s Mental Health

Outdoor Enjoyment Linked to Less Inflammation

Link Between Heart Disease, Depression, and Inflammation Found

Embryonic Pathways Found to Balance the Adult Mind

How AI “Brain States” Decode Reality

Early Imaginative Play Predicts Better Mental Health

Midlife Fitness Delays Chronic Disease by Years

Subscribe