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inflammation

·October 13, 2024·5 min read

Liver Inflammation Linked to Cognitive Decline in Aging

New research explores how chronic liver inflammation may lead to brain inflammation and cognitive decline as people age. Through the study of necroptosis, a form of cell death that triggers inflammation, researchers are examining how inflammatory molecules released by the liver impact the brain. Early findings suggest that blocking necroptosis reduces liver and brain inflammation, potentially helping to maintain cognitive function.

Featured Neurology Neuroscience

·October 8, 2024·5 min read

Brainstem Inflammation Linked to Long-Covid Symptoms

New research shows that severe Covid-19 infection can cause inflammation in the brainstem, potentially leading to prolonged symptoms like fatigue, breathlessness, and anxiety. Using ultra-high-resolution 7-Tesla MRI scanners, scientists observed specific brainstem areas associated with these symptoms, highlighting how immune response post-infection might affect brain health.

Featured Genetics Neuroscience Psychology

·October 5, 2024·5 min read

Gene Activity in Depression Linked to Immune System and Inflammation

A new study reveals that inflammation and immune system activation are closely linked to major depressive disorder (MDD), particularly in those resistant to standard antidepressants. Researchers analyzed gene expression in people with depression, finding increased immune-related gene activity, especially in those with higher inflammation.

Featured Neuroscience

·October 2, 2024·5 min read

57% of Americans Have Pro-Inflammatory Diets

Nearly 60% of Americans consume pro-inflammatory diets, increasing their risk for heart disease, cancer, and other health issues. The research shows that Black Americans, men, and people with lower incomes are more likely to follow diets high in inflammatory foods.

Featured Genetics Neurology Neuroscience

·September 30, 2024·5 min read

Genetic Variants Linked to Alzheimer’s Trigger Inflammation in Females

Researchers have discovered that two genetic variants, APOE4 and TREM2 R47H, together cause a harmful inflammatory response in brain immune cells, particularly in females. This response leads to more severe brain damage, including tau protein clumps, which are linked to Alzheimer’s disease progression.

Featured Genetics Neurology Neuroscience

·August 28, 2024·4 min read

Increase in Protein Linked to Salt Intake Implicated in Multiple Sclerosis

Researchers have uncovered that increased levels of the protein PRDM1-S, triggered by high salt intake, disrupt immune regulation and contribute to autoimmune diseases like multiple sclerosis (MS). This discovery reveals how environmental factors, such as diet, can influence genetic mechanisms, leading to T cell dysfunction. The findings suggest that targeting PRDM1-S could lead to new treatments for a range of autoimmune disorders.

Featured Neuroscience Psychology

·August 21, 2024·5 min read

Childhood Inflammation Linked to Later Mental Health Risks

Children with persistent inflammation are at a higher risk of developing mental health disorders like psychosis and depression in early adulthood. A study found that elevated inflammation markers, particularly around age 9, significantly increase the risk of these disorders, as well as cardiometabolic diseases such as insulin resistance. The research suggests that early-life inflammation could be a critical factor in later mental and physical health issues, prompting the need for further investigation into its role.

Featured Genetics Neuroscience

·July 17, 2024·6 min read

Blocking Inflammation Protein Extends Lifespan

Researchers discovered that inhibiting the protein IL-11 extends the lifespan of mice by up to 25%. The treatment also reduces cancer and diseases related to aging.

Featured Neurology Neuroscience

·July 12, 2024·6 min read

Infection Brain Inflammation Triggers Muscle Weakness

A new study reveals how brain inflammation from infections and neurodegenerative diseases causes muscle weakness by releasing the IL-6 protein. Researchers found that IL-6 travels from the brain to muscles, reducing their energy production and function. This discovery could lead to treatments for muscle wasting in diseases like Alzheimer's and long COVID. Blocking the IL-6 pathway may prevent muscle weakness associated with brain inflammation.

Featured Neurology Neuroscience

·July 5, 2024·5 min read

Early Inflammation Linked to Midlife Cognitive Decline

A new study finds that higher inflammation in young adulthood is associated with reduced cognitive function in midlife. Researchers discovered that inflammation due to factors like obesity and smoking can impact memory and processing speed.

Featured Neuroscience

·June 10, 2024·4 min read

Placental Cells Indicate Fetal Brain Health

Fetal placental macrophages can serve as indicators of fetal brain microglia health, which are crucial for brain development. Immune activation in pregnant women, such as from infections or obesity, can negatively affect fetal brain development. The study used mouse models and found that male fetuses are more affected by maternal obesity than females. This research opens avenues for early identification and intervention in neurodevelopmental disorders.

Featured Neuroscience

·June 3, 2024·2 min read

Aspirin Eases Inflammation from Sleep Loss

Low-dose aspirin reduces inflammatory responses caused by sleep restriction. Compared to a placebo, aspirin lowered interleukin-6, COX-1/COX-2 cells, and C-reactive protein levels.

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inflammation

Liver Inflammation Linked to Cognitive Decline in Aging

Brainstem Inflammation Linked to Long-Covid Symptoms

Gene Activity in Depression Linked to Immune System and Inflammation

57% of Americans Have Pro-Inflammatory Diets

Genetic Variants Linked to Alzheimer’s Trigger Inflammation in Females

Increase in Protein Linked to Salt Intake Implicated in Multiple Sclerosis

Childhood Inflammation Linked to Later Mental Health Risks

Blocking Inflammation Protein Extends Lifespan

Infection Brain Inflammation Triggers Muscle Weakness

Early Inflammation Linked to Midlife Cognitive Decline

Placental Cells Indicate Fetal Brain Health

Aspirin Eases Inflammation from Sleep Loss

Brain Cells Tune to Multiple Rhythms Like a Neural Radio

Neglecting Dads’ Mental Health May Harm Kids’ Development

How the Brain Actively Removes Unwanted Memories

Mitochondrial Link to Cerebellar Decline in MS

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