UV light from sunbathing and mosquito-borne diseases activate NLRP1 through p38, triggering skin inflammation.
COVID-19 infection activates the same inflammatory response in the brain as Parkinson's disease, a new study reports.
SARM, an ancient immune protein previously implicated in apoptosis, is a key immune regulator in peripheral immune cells. The finding could help in the development of treatments for a range of diseases, including Alzheimer's, cancer and diabetes.
Researchers report snacking can raise inflammation and contribute to metabolic diseases.
Findings could help guide researchers to develop new drugs to treat Multiple Sclerosis and other neurological diseases.
Sleep may be regulated by inflammasome NLRP3, researchers report.
Researchers have discovered a molecule, MCC950, which suppresses the NLRP3 inflammasome.