Secondary infections and novel inflammatory events, even ones that occur external to the brain, amplify the brain's immune response and detrimentally impact cognition in mouse models of Alzheimer's disease.
Study identifies a specific type of immune cell that induces inflammation in herpes simplex virus (HSV) encephalitis.
Microglia help limit infection to the olfactory bulb and protects neurons from damage that could occur as a result of viral infection.
Infectious disease experts report between 40% and 70% of adults could become infected with coronavirus during the outbreak. In a new interview, Dr. Lipsitch, head of Harvard's T.H. Chan School of Public Health's Center for Communicable Disease Dynamics, discusses the risks and spread potential of COVID-19, and addresses how the infection could impact children's' health.
Vaping e-cigarettes modulates the oral microbiome and increases the abundance of pathobionts. The aerosols in vaping products alter the host response, prompting gum inflammation and making epithelial cells in the mouth susceptible to infection.
Immune molecules produced during infection influence the social behaviors of mouse models of autism spectrum disorder. The findings may shed light on why some children on the autism spectrum experience a temporary reduction in behavioral symptoms when they have a fever.
Previous studies have documented how infection during pregnancy can increase the risk of ASD and a range of psychiatric disorders in the offspring. A new study reveals how maternal infections can affect neural development and how the timing of infection plays a critical role in elevating the risks of mental health conditions.
Mice infected with bacteria that cause mild intestinal infections exhibited Parkinson's like symptoms later in life. The findings provide a pathophysiological model in which intestinal infections may act as a trigger for Parkinson's disease.