FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·June 8, 2021·4 min readImmune Cell Behavior That Plays a Key Role in Alzheimer’s Disease DiscoveredSustained microglia activation leads to the cells becoming senescent. This leads to an accelerated accumulation of amyloid in the brain, influencing the early stages of Alzheimer's development.Read More
FeaturedNeurologyNeuroscience·June 3, 2021·2 min readSecondary Infections Inflame the Brain, Worsening Cognition in Alzheimer’s DiseaseSecondary infections and novel inflammatory events, even ones that occur external to the brain, amplify the brain's immune response and detrimentally impact cognition in mouse models of Alzheimer's disease.Read More
FeaturedNeurologyNeuroscience·June 3, 2021·5 min readThe Skull Is an Unexpected Source of Brain ImmunityImmune cells in the meninges come from bone marrow in the skull and migrate to the brain through special channels without passing through the blood. These immune cells help to guard the brain and spinal cord against inflammation and infection.Read More
FeaturedNeurologyNeuroscience·May 16, 2021·4 min readAnesthetic May Affect Tau Spread in the Brain to Promote Alzheimer’s Disease PathologySevoflurane, an anesthetic, causes tau to leave neurons and enter microglia. This stimulates the production of interleukin-6, leading to inflammation and cognitive impairment.Read More
FeaturedNeurologyNeuroscience·May 13, 2021·3 min readFood Dyes May Cause Disease When the Immune System Is DysregulatedMice with cytokine IL-23 dysregulation who consumed foods containing the artificial colorants FD&C Red 40 and Yellow developed colitis, a new study reports.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience ArticlesPain·May 13, 2021·6 min readMissing Piece of the Lyme Disease Puzzle IdentifiedNapA, a protein associated with the peptidoglycan of Borrelia burgdorferi, plays an amplifying role in causing inflammation in Lyme disease associated arthritis.Read More
FeaturedNeurologyNeuroscience·May 13, 2021·3 min readTeam Tests Medical Marijuana as Possible Therapy for Chronic ItchA new case study reveals medical marijuana may provide rapid relief for sufferers of chronic itch. Researchers say THC attaches itself to brain receptors that influence the nervous system. This reduces inflammation and nervous system activity, leading to a reduction in itch sensation.Read More
FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology·May 12, 2021·4 min readBrain Immune System Linked to PsychosisA link has been identified between psychosis and a genetic change that alters the immune system in the brain. Researchers found people with psychosis associated with bipolar disorder had decreased expression of GRK3. This led to an increased amount of kynurenic acid in the brain.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·May 11, 2021·4 min readTumor-Promoting Immune Cells Retrained to Fight Most Aggressive Type of Brain CancerCombining αGITR antibodies with ICBs resulted in stronger survival benefits in mouse models of human glioblastoma brain cancer.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·April 29, 2021·5 min readInflammation Seen in Earliest Stages of Parkinson’s Disease, and It Is Different Between Men and WomenStudy finds evidence of inflammation in the blood of patients during the early stages of Parkinson's disease. The findings support the theory that inflammation is a driver of the neurodegenerative disorder. The effect was most noticed in women with Parkinson's.Read More
FeaturedNeurosciencePsychology·April 28, 2021·6 min readStress Slows the Immune Response in Sick MiceNoradrenaline impairs immune response by inhibiting the movement of leukocytes to different tissue.Read More
ElectrophysiologyFeaturedNeurosciencePsychology·April 24, 2021·6 min readThe Immune Link Between a Leaky Blood-Brain Barrier and SchizophreniaPeople with schizophrenia and other neuropsychiatric disorders may have a more permissive blood-brain barrier which allows the immune system to become more actively involved in the central nervous system. The resulting inflammation may contribute to the clinical manifestation of psychosis-like symptoms.Read More
