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immune system

·January 2, 2026·7 min read

Immune Signal Ratio May Predict Progressive Multiple Sclerosis

A long-term study has identified a potential biomarker that could help detect which patients are progressing toward more severe forms of multiple sclerosis. Researchers discovered that a high ratio of CXCL13 to BAFF indicates compartmentalized inflammation in the leptomeninges, a hallmark of progressive MS.

Featured Neurology Neuroscience

·October 20, 2025·6 min read

First Signs of Multiple Sclerosis Found Years Before Symptoms

Researchers have traced the earliest stages of multiple sclerosis (MS), showing that the immune system begins attacking the brain up to seven years before diagnosis. By analyzing over 5,000 blood proteins, they identified molecular signs of damage to myelin—the protective sheath around nerve fibers—long before symptoms emerge.

This shows a brain, immune cells, and a scale.

Featured Neurology Neuroscience

·September 18, 2025·5 min read

Alzheimer’s Research Shifts Toward Immune System Balance

Alzheimer’s disease affects over 55 million people worldwide and has long been linked to toxic protein buildup and chronic inflammation in the brain. A new review shows that adaptive immune cells—T and B cells—also play a crucial role, sometimes worsening brain damage, sometimes offering protection.

Autism Featured Neuroscience

·August 20, 2025·4 min read

Gut Bacteria and Immune Cells May Drive Autism

Researchers have uncovered a critical connection between the gut microbiota, the immune system, and autism spectrum disorder (ASD). In a germ-free genetic mouse model, removal of gut microbes reduced autism-like behaviors and lowered brain inflammation, showing that microbes may play a dominant role in driving symptoms.

This shows a neuron attached to a flower, as though to imply the olfactory implications associated with Alzheimer's.

Featured Neurology Neuroscience

·August 17, 2025·4 min read

Immune Attack on Smell Pathways May Signal Early Alzheimer’s

A fading sense of smell may be one of the earliest warning signs of Alzheimer’s disease, and new research reveals why. Scientists found that microglia, immune cells in the brain, mistakenly remove nerve fibers connecting the locus coeruleus and olfactory bulb—two regions essential for processing odors.

Featured Neuroscience

·June 3, 2025·7 min read

Ibudilast Fails to Beat Placebo in Alcoholism Trial, Except in Women

A recent clinical trial found that ibudilast, a drug once promising for alcohol use disorder, was no more effective than a placebo overall. While all participants reduced their drinking, women on ibudilast showed a greater drop in drinks per day, hinting at a gender-specific benefit.

Featured Neuroscience

·June 1, 2025·7 min read

T Cells Found Living in Healthy Brains

Contrary to long-standing beliefs, T cells—key immune cells—have been discovered in the healthy brains of both mice and humans. These cells, previously thought to only enter the brain during disease, were most concentrated in a region that regulates hunger and thirst.

This shows a person standing in sunlight.

Featured Neurology Neuroscience

·May 26, 2025·3 min read

Daylight Boosts Immune Defense

Researchers have discovered that daylight enhances the infection-fighting power of neutrophils, the most abundant white blood cells in the body. Using transparent zebrafish, scientists observed that these immune cells contain internal circadian clocks that are activated by light, boosting their bacterial-killing ability during the day.

Featured Neurology Neuroscience

·May 17, 2025·6 min read

Babies Fight COVID Differently Than Anyone Else

Infants hospitalized with severe COVID-19 mount an immune response that looks entirely different from that of adults or older children. Researchers found both interferon responses and inflammation were elevated simultaneously—something never before observed in other viral infections.

Brain Cancer Featured Neurology Neuroscience

·May 13, 2025·7 min read

CAR-T Brain Fog Mirrors Chemo and COVID

Patients receiving CAR-T cell therapy often report brain fog, and new research shows this cognitive impairment stems from the therapy itself, not just the cancer or other treatments. A mouse study revealed that CAR-T-induced immune responses activate brain microglia, triggering inflammation that damages myelin-producing cells, reducing signal efficiency in the brain.

Featured Genetics Neuroscience

·May 8, 2025·4 min read

Bigger Brains and Strong Immunity Linked to Longer Lifespans

New research reveals that mammals with larger brains and more robust immune systems tend to live longer lives. By studying 46 species, scientists found a clear link between maximum lifespan and the expansion of immune-related gene families.

Featured Neuroscience

·May 8, 2025·4 min read

How Brain Signals Shape Its Protective Waste Disposal Network

The brain’s meningeal lymphatic system plays a key role in clearing waste and transporting immune cells, but until now, how it develops was unclear. Using zebrafish and advanced imaging, researchers revealed that neural activity regulates this system by influencing specialized glial cells that release Vegfc, a key growth factor.

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immune system

Immune Signal Ratio May Predict Progressive Multiple Sclerosis

First Signs of Multiple Sclerosis Found Years Before Symptoms

Alzheimer’s Research Shifts Toward Immune System Balance

Gut Bacteria and Immune Cells May Drive Autism

Immune Attack on Smell Pathways May Signal Early Alzheimer’s

Ibudilast Fails to Beat Placebo in Alcoholism Trial, Except in Women

T Cells Found Living in Healthy Brains

Daylight Boosts Immune Defense

Babies Fight COVID Differently Than Anyone Else

CAR-T Brain Fog Mirrors Chemo and COVID

Bigger Brains and Strong Immunity Linked to Longer Lifespans

How Brain Signals Shape Its Protective Waste Disposal Network

Hippocampus Predicts Rewards by Reorganizing Memories

Memory Rewritten: Study Finds No Clear Line Between Episodic and Semantic Retrieval

Brain Stimulation Method Can Evaluate Consciousness in Alzheimer’s Disease

Early Intervention Helps Most Autistic Children Acquire Spoken Language

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