Changes in fetal microglia caused as a result of maternal inflammation could contribute to the development of schizophrenia, autism, and other psychiatric or developmental disorders. Read More
Researchers have identified a direct cellular interaction between the nervous system and the immune system. Pain sensing neurons around the lymph nodes can modulate lymph node activity. Read More
The spike protein of SARS-CoV-2 can pass through the blood-brain barrier of mice. The protein likely causes the brain to release cytokines and spark neuroinflammation. The findings add to growing evidence that COVID-19 can enter the brain of those infected by the virus. Read More
Schizophrenia may, in part, be caused by immune system dysfunction, a new study reports. Treatment with Methotrexate, a drug commonly prescribed for autoimmune disorders like R.A, produced positive effects against some prominent schizophrenia symptoms. Read More
Neural mapping of the enteric nervous system reveals how fetal neurons form during development. The process of neural development in the ENT follows different principal to the development of neurons in the brain. Read More
Study reveals the gut microbiome directly influences the makeup of the human immune system. Researchers found the concentration of different types of immune cells in the blood change in the presence of different bacterial strains in the gut. Read More
Study finds signs of IgA antibodies in the cerebrospinal fluid of patients with multiple sclerosis during a flare-up of the disease, but not when the patients are in remission. The findings suggest gut immune cells are involved in relapse episodes of multiple sclerosis. Read More
Poor sleep and inadequate oxygen supply associated with obstructive sleep apnea appears to affect cytokines. This could explain the link between OSA and an increased risk of autoimmune disorders, such as rheumatoid arthritis. Read More
Behavioral changes in those with T.gondii infection could be linked to lower levels of norepinephrine. Norepinephrine also controls inflammation. Both neuroinflammation and norepinephrine are associated with a range of psychiatric disorders including schizophrenia and ADHD. Read More
Study identifies inflammatory mechanisms and cellular activity in the amygdala that drives alcohol addiction in mice. Chronic alcohol exposure compromises immune cells in the brain, driving anxiety and alcohol consumption that may lead to the development of AUD. Read More
TEPP-46, a drug developed for the treatment of cancer and showed promise for the treatment of multiple sclerosis, could make MS symptoms worse, a new study reports. The drug appears to redirect inflammation away from the spinal cord and directly into the brain. Read More
YTHDF2 is a key protein that assists in creating healthy blood cells by regulating the body's inflammatory response. Read More
