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immune system

·July 2, 2026·10 min read

Stress Accelerates Immune Aging by Altering the Microbiome

Chronic psychological stress suppresses activity in the prefrontal cortex and periaqueductal gray, triggering a downstream depletion of gut Lactobacillus reuteri and its anti-aging metabolite spermidine. This biochemical crash directly accelerates the aging of hematopoietic stem cells in the bone marrow, mapping a novel brain-gut-bone axis for stress-induced immune decay.

Featured Neurology Neuroscience

·June 29, 2026·11 min read

Viral Infection Found to Trigger Parkinson’s Brain Damage

A new study demonstrates that a non-toxic viral infection via TMEV triggers the exact dopaminergic neuron destruction and progressive gait degradation seen in human Parkinson's disease, establishing a vital new animal model to study the natural environmental origins of neurodegeneration.

Featured Neurology Neuroscience

·June 18, 2026·8 min read

Aging Immune Networks Linked to Parkinson’s Progression

Researchers secured a $9 million grant to study how immune-cell aging impacts Parkinson’s disease.

Brain Cancer Featured Neurology Neuroscience

·May 17, 2026·6 min read

Study Maps Brain Immune Cells to Block Melanoma Metastasis

Can the brain's own immune system be engineered to lock out invading cancer cells? A multidisciplinary research team is investigating new myeloid-focused strategies to prevent melanoma from metastasizing to the brain.

Featured Neuroscience

·March 25, 2026·8 min read

How the Gut Tells the Brain to Stop Eating

Researchers have discovered the molecular pathway connecting the gut immune system to the brain. By mapping how tuft cells signal the vagus nerve, the study explains why parasitic infections and gut issues cause a lingering loss of appetite.

Featured Neuroscience

·February 12, 2026·7 min read

Beyond the Blood-Brain Barrier: New “Smart Gate” Shielding the Brain

For decades, we believed we understood the fortifications protecting our most vital organ. But a team of Belgian researchers just proved that the brain has been hiding a secret 'smart gate.' By identifying a unique population of 'base barrier cells' within the choroid plexus, scientists have uncovered a dynamic secondary shield that dictates exactly what—and who—gets access to the brain’s inner sanctum. This discovery doesn't just rewrite anatomy textbooks; it reveals exactly how systemic infections might be 'leaking' into our central nervous system, triggering neuroinflammation and disease.

Featured Neurology Neuroscience

·January 2, 2026·7 min read

Immune Signal Ratio May Predict Progressive Multiple Sclerosis

A long-term study has identified a potential biomarker that could help detect which patients are progressing toward more severe forms of multiple sclerosis. Researchers discovered that a high ratio of CXCL13 to BAFF indicates compartmentalized inflammation in the leptomeninges, a hallmark of progressive MS.

Featured Neurology Neuroscience

·October 20, 2025·6 min read

First Signs of Multiple Sclerosis Found Years Before Symptoms

Researchers have traced the earliest stages of multiple sclerosis (MS), showing that the immune system begins attacking the brain up to seven years before diagnosis. By analyzing over 5,000 blood proteins, they identified molecular signs of damage to myelin—the protective sheath around nerve fibers—long before symptoms emerge.

This shows a brain, immune cells, and a scale.

Featured Neurology Neuroscience

·September 18, 2025·5 min read

Alzheimer’s Research Shifts Toward Immune System Balance

Alzheimer’s disease affects over 55 million people worldwide and has long been linked to toxic protein buildup and chronic inflammation in the brain. A new review shows that adaptive immune cells—T and B cells—also play a crucial role, sometimes worsening brain damage, sometimes offering protection.

Autism Featured Neuroscience

·August 20, 2025·4 min read

Gut Bacteria and Immune Cells May Drive Autism

Researchers have uncovered a critical connection between the gut microbiota, the immune system, and autism spectrum disorder (ASD). In a germ-free genetic mouse model, removal of gut microbes reduced autism-like behaviors and lowered brain inflammation, showing that microbes may play a dominant role in driving symptoms.

This shows a neuron attached to a flower, as though to imply the olfactory implications associated with Alzheimer's.

Featured Neurology Neuroscience

·August 17, 2025·4 min read

Immune Attack on Smell Pathways May Signal Early Alzheimer’s

A fading sense of smell may be one of the earliest warning signs of Alzheimer’s disease, and new research reveals why. Scientists found that microglia, immune cells in the brain, mistakenly remove nerve fibers connecting the locus coeruleus and olfactory bulb—two regions essential for processing odors.

Featured Neuroscience

·June 3, 2025·7 min read

Ibudilast Fails to Beat Placebo in Alcoholism Trial, Except in Women

A recent clinical trial found that ibudilast, a drug once promising for alcohol use disorder, was no more effective than a placebo overall. While all participants reduced their drinking, women on ibudilast showed a greater drop in drinks per day, hinting at a gender-specific benefit.