Cysteine leukotriene receptor 2 appears to be a key player in chronic itch, a new study reports. Read More
Chronic viral infections have a profound and lasting impact on the immune system in a similar way to aging. Chronic inflammation that occurs as a result of immune system dysregulation is often seen in diseases associated with aging. Read More
The protein Arginase-2 works through mitochondria to reduce inflammation. The findings could lead to new treatments for diseases associated with neuroinflammation, including multiple sclerosis and rheumatoid arthritis. Read More
Study identifies 40 genes in mice that actively suppress axon regeneration in the central nervous system. Read More
Study finds the immune system links personality to the long-term risk of mortality. Those who score higher on the personality trait of conscientiousness tend to live longer because their immune systems have lower levels of interleukin-6. Read More
Immune cells in the meninges monitor fluid released from the brain. If the fluid contains signs of infection, disease, or damage, the immune cells initiate an immune response to tackle the problem. Read More
Regulatory T cells expand in the first three weeks of life in breastfed babies, and are twice as abundant than in bottle-fed babies. Specifically, the bacterias Veillonella and Gemella are more abundant in the guts of breastfed babies. Veillonella and Gemella supportthe function of regulatory T cells. Read More
Treatment with LAU-0901, a synthetic molecule that blocks pro-inflammatory platelet-activating factor, in addition to aspirin-triggered NPD1, reduced the size of damage areas in the brain, initiated repair mechanisms, and improved behavioral recovery following ischemic stroke. Read More
Biologically active polysaccharides from red algae known as carrageenan appear to suppress the activity of peritoneal phagocytes in mice, generating an immunosuppressant effect. Read More
Changes in fetal microglia caused as a result of maternal inflammation could contribute to the development of schizophrenia, autism, and other psychiatric or developmental disorders. Read More
Researchers have identified a direct cellular interaction between the nervous system and the immune system. Pain sensing neurons around the lymph nodes can modulate lymph node activity. Read More
The spike protein of SARS-CoV-2 can pass through the blood-brain barrier of mice. The protein likely causes the brain to release cytokines and spark neuroinflammation. The findings add to growing evidence that COVID-19 can enter the brain of those infected by the virus. Read More
