Patients who experienced cognitive impairments, or brain fog, following COVID-19 infection had abnormalities in their cerebrospinal fluid. Researchers say the overstimulation of the immune system as a result of COVID may be the cause of cognitive deficits.
The risk of developing mutliple sclerosis increases 32 fold following Epstein-Barr virus infection.
Age-related macular degeneration and lupus share a common contributor to inflammation. The findings could help researchers develop new treatments for those conditions, and other conditions associated with inflammation.
An increased white blood cell count has been linked to increased depression polygenic scores. The findings highlight the importance of the immune system in the development and severity of depression.
Microglia, a key immune cell in the brain, appears to mediate the relationship between the gut microbiome and amyloid-beta deposits in male mouse models of Alzheimer's disease.
A drug currently being tested in cancer clinical trials appears to prevent dysfunction in an immune cell signaling pathway associated with Alzheimer's disease. Blocking the pathway could prevent Alzheimer's from developing and slow the progression of symptoms for those who already have the disease.
Researchers examine how neuroimmune interactions promote brain plasticity and shed new light on how neuroimmune activity may have implications for a range of disorders, including neurological changes experienced by COVID-19 survivors.
Glial cells coordinate immune responses in the gut following infection. Researchers report glial cells could be targets for therapeutics to treat inflammatory bowel disorders.
Study reveals microglia play an important role in the maintenance of blood delivery to the brain. The findings may prove important to the study and treatment of cognitive decline, dementia, and stroke.