Immune system can slow degenerative eye disease: Mouse study
Study reveals C3, which can cause damage in some eye diseases, may help to slow the progression of retinitis pigmentosa.... Read More...
immune system
How is a mother’s immunity transferred to her baby?
Study reveals how a pregnant woman's vaccine-induced immunities are transferred to her offspring via the placenta. The findings have positive implications for the development of new, more effective maternal vaccines.... Read More...
Women caught in a pickle by their own immune systems
Pregnancy Compensation Hypothesis may explain why women are more prone to developing autoimmune diseases, like multiple sclerosis and lupus, than men.... Read More...
Genetics influence how protective childhood vaccines are for individual infants
A large, genome-wide study in children reveals genetic variants associated with differing levels of antibodies produced as a result of three common childhood vaccinations. Researchers identified two genetic loci associated with the persistence of vaccine-induced immunity following early life vaccinations. The results may help clinicians tailor personalized vaccine schedules to maximize the effectiveness of immunizations.... Read More...
Promising treatment option for Complex Regional Pain Syndrome
Blocking the activity of interleukin-1 in mouse models of complex regional pain syndrome (CRPS) helped reverse symptoms. Researchers say patients with CRPS should respond to immune-based treatments which reduce some of the disease features.... Read More...
Memory Preserver: Researchers Develop Vaccine That Could Protect Against Alzheimer’s
Researchers have engineered a vaccine using virus-like particles that target Tau tangles in mouse models of Alzheimer's disease. Following the administration of the vaccine, the mice developed antibodies that cleared tau proteins, with the response lasting for a month. The mice also showed improvements in memory based tests and had less brain shrinkage than their peers who did not receive the vaccine. This suggests the vaccine prevented apoptosis. Researchers hope to move the vaccine to human clinical trials in the future.... Read More...
Study finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse study
PTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals.... Read More...
Scientists discover how hepatitis C ‘ghosts’ our immune system
Hepatitis C virus increases the expression of SOCS, dulling the normal immune system response to viral infections. This may explain why Hepatitis C 'hides' in the immune system, leading to a lack of diagnosis in those suffering the infection. ... Read More...
12 genes at the root of multiple sclerosis identified
12 genes associated with familial multiple sclerosis have been identified. The findings provide a molecular rationale for the chronic inflammation, demyelination and neurodegeneration associated with MS. Identifying new genetic targets could help with the development of novel treatments to prevent multiple sclerosis in those with a genetic risk.... Read More...
Nanotechnology treatment reverses multiple sclerosis in mice
Extracting nanosized exosomes from bone marrow stem cells and injecting them into mice, researchers reverse symptoms of multiple sclerosis.... Read More...
How chronic inflammation may drive down dopamine and motivation
Computational model sheds light on the impact chronic, low-grade inflammation has on the mesolimbic dopamine system and motivational impairments.... Read More...
Immune cells determine how fast certain tumors grow
Immune cells can accelerate the growth of cancerous tumors in mouse models of NF1.... Read More...