A two-week course of CBD helps normalize and restore the function of two proteins associated with reducing amyloid-beta accumulation in mouse models of familial Alzheimer's disease. CBD also reduces levels of IL-6, an immune protein associated with inflammation in Alzheimer's patients.
Anacardic acid, a compound found in cashew shells, promotes the repair of myelin. The findings could have positive implications for the treatment of diseases, such as multiple sclerosis, that are characterized by demyelination.
Dropping the level of the IL-33 immune molecule increased the number of synapses in the brain. In older mice, ramping up IL-33 helped push the number of new synapses toward a more youthful state.
Activating group 2 innate lymphoid cells in aging brains helps improve memory in mice. The findings could help in the development of treatments for neurodegenerative diseases associated with aging.
A new PNAS study reveals why men are less likely to develop multiple sclerosis than women. According to researchers, a 'guardian molecule' that is triggered by testosterone appears to have a protective effect in men. When female mice were treated with the molecule, their symptoms of the disease were eliminated.
Researchers investigate how synaptic pruning occurs during development in hopes of discovering how neurodevelopmental and psychiatric disorders occur.
Researchers have successfully blocked an immune system protein with an antibody to stop itching associated with poison ivy contact.
Injections of IL-33 appear to rescue contextual memories and reduce amyloid beta deposits in mouse models of Alzheimer's disease.
Researchers report IL-33 can reduce memory and cognitive problems associated with Alzheimer's disease within one week of treatment in mice. Additionally, IL-33 can reduce the number and size of amyloid plaques.