A specific pathway of nerves and cells that link the gut to the brain may be responsible for chronic gut pain. Chronic gut pain is commonly associated with IBS, and mental health disorders including anxiety and depression.
Study reveals a link between IBS and an increased risk of developing mental health disorders including anxiety, depression, and suicidal ideation. Researchers say identifying and treating mental health comorbidities in those with IBS improves the quality of life for sufferers.
Consuming green vegetables and adding a daily chlorophyllin supplement helps alleviate symptoms of inflammatory bowel disease, researchers report. Additionally, chlorophyllin supplements help significantly reduce mortality risks associated with IBD.
The vascular barrier in the choroid plexus locks down access to the brain in response to gut inflammation that causes IBD. The dysregulated activity of the gut-brain vascular axis appears to protect the brain from inflammation. However, the mechanism may increase the risk of both cognitive and mental health problems associated with IBD.
Depression may be a new biomarker for the onset of specific bowel conditions, researchers report. The study found those with digestive disorders such as IBS, Crohn's disease, and ulcerative colitis were more likely to be diagnosed with depression up to nine years prior to being diagnosed with bowel conditions.
Infections in the intestine may contribute to irritable bowel syndrome (IBS) by damaging the gut's nervous system. Researchers explore why neurons in the gut die as a result of infection and how the immune system normally protects them. The findings could provide new avenues of treatment for IBS.
Study reveals a link between obesity and chronic diarrhea, independent of lifestyle, diet, and other medical conditions. Those who are obese are 60% more likely to experience bouts of chronic diarrhea. A possible explanation could be the link between obesity and low-grade inflammation, which may trigger diarrhea more frequently.
Mice that experienced early life stress and later developed irritable bowel syndrome had significantly higher levels of intestinal stem cells and enterochromaffin (EC). Additionally, the mice expressed elevated secretion of serotonin as a result of the increased EC cell density.
Eating processed food which contains Propionic Acid (PPA) during pregnancy may affect neural stem cell development in the fetal brain. Excessive PPA reduces the number of neurons and over-produces glial cells, causing inflammation. Additionally, PPA shortens neural pathways. The combination of damaged pathways and reduced neurons may be associated with behavioral deficits associated with ASD.