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          Huntington’s disease

          This shows neurons
          FeaturedNeurologyNeuroscience
          ·January 20, 2023·6 min read

          How Huntington’s Disease Affects Different Neurons

          Researchers have identified how two different populations of neurons in the striatum are affected differently in Huntington's disease. The neurodegeneration of one of these populations leads to motor defects while damage to the other population located in striosomes may account for mood disorders associated with the early stages of Huntington's.
          Read More
          This shows neurons
          FeaturedGeneticsNeurologyNeuroscience
          ·December 12, 2022·4 min read

          CRISPR Technology Improves Huntington’s Disease Symptoms in Models

          Using CRISPR gene editing to directly target RNA, researchers eliminated toxic protein buildup associated with Huntington's disease while not disrupting other human genes.
          Read More
          This shows neurons
          FeaturedNeurologyNeuroscience
          ·October 28, 2022·6 min read

          Cellular Housekeeping Process Implicated in Huntington’s Disease

          Study reveals how aging impairs autophagy and how enhancing autophagy can prevent cells from dying in Huntington's disease.
          Read More
          This shows a neuron
          FeaturedGeneticsNeurologyNeuroscience
          ·September 27, 2022·4 min read

          Study Probes Huntington’s Disease Protein’s Function in Injured Neurons

          The Huntington's disease protein huntingtin may have a role external to the neurodegenerative disease. Researchers say Huntingtin is involved in neural injury and regeneration.
          Read More
          This shows neurons
          FeaturedNeurologyNeuroscience
          ·September 19, 2022·3 min read

          Discovery of the Causes of Brain Dysfunction in Patients With Huntington’s Disease

          Researchers discovered decreased function in a protein critical for synaptic function in those with Huntington's disease.
          Read More
          This shows a brain
          FeaturedGeneticsNeurologyNeuroscience
          ·August 17, 2022·3 min read

          Reprogramming Human Skin Cells Into Aged Neurons to Study Neurodegenerative Disorders

          Converting skin cell samples into neurons helps researchers gain a better understanding of the mechanisms of Huntington's disease.
          Read More
          This shows a brain and red blood cells
          FeaturedNeurologyNeuroscience
          ·February 15, 2022·7 min read

          A New Atlas of Cells That Carry Blood to the Brain

          Researchers have created a comprehensive atlas of cell types in the brain's cerebrovascular system.
          Read More
          This shows neurons
          FeaturedGeneticsNeurologyNeuroscience
          ·November 29, 2021·5 min read

          Why Some People Experience Early Onset Neurodegenerative Diseases

          A new study sheds light on the genetic causes of a range of neurodegenerative disorders, including ALS, Parkinson's disease, and Huntington's disease, and determines factors that impact the age of onset as well as disease severity.
          Read More
          This shows a cluster of cells
          FeaturedNeurologyNeuroscience
          ·October 5, 2021·4 min read

          Study Detects Origins of Huntington’s Disease in Two-Week-Old Human Embryos

          Synthesizing a human embryo from stem cells and using gene editing to insert the Huntingtin gene, researchers found the mutation affected the size of germ layers compared to the control embryos. Findings suggest Huntington's disease may be a neurodevelopmental disorder that presents as a neurodegenerative disease later
          Read More
          This shows a brain
          FeaturedNeurologyNeuroscience
          ·July 15, 2021·4 min read

          Autophagy May Be the Key to Finding Treatments for Early Huntington’s Disease

          Disruption of autophagy may be at the root of the cognitive deficits experienced by those with Huntington's disease.
          Read More
          This shows neurons. The caption best describes the image
          FeaturedGeneticsNeurologyOpen Neuroscience Articles
          ·March 6, 2021·4 min read

          Huntington’s Disease Driven by Slowed Protein-Building Machinery in Cells

          The mutated huntingtin protein slows ribosome movement and decreases protein synthesis.
          Read More
          This is a graphic abstract from the study
          FeaturedGeneticsNeurologyNeuroscience
          ·January 7, 2021·6 min read

          Effects of Huntington’s Disease Mutation May Begin in Childhood

          A new study adds to the growing body of evidence that the origin of Huntington's disease is rooted in childhood. Researchers say the HTT gene mutation affects both brain and body growth during development, and the increased susceptibility of brain cell death begins early in life.
          Read More
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          Exercise Mitigates Genetic Risk for Type 2 Diabetes

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          Boosting Infant Brains: Parental Speech Enhances Baby’s Development

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          Mosaic Mutations Reveal New Insights into Bipolar Disorder

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          Visualizing Brain Synapse Strength With AI

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