Scientists recreate blood-brain barrier defect outside the body
Using induced pluripotent stem cells derived from patients with neurodegenerative disorders, researcher recreated the blood-brain barrier inside Organ-Chips. ... Read More...
Huntington’s disease
How mutations lead to neurodegenerative disease
Genetic mutations which lead to abnormal RNA in regions of repeat DNA sequences set off anti-viral like inflammatory responses. This leads to apoptosis and ultimately trigger the onset of neurodegenerative diseases. ... Read More...
Circadian clock plays unexpected role in neurodegenerative diseases
Disrupted sleep patterns may help to protect neurons in the brain in Huntington's disease. ... Read More...
Speeding Up Genetic Diagnosis of Huntington’s Disease
Researchers have developed a method to determine the length of mutated genes associated with Huntington's disease quickly and easily.... Read More...
Regulating Microglial Activity May Reduce Inflammation in Neurodegenerative Diseases
Researchers report activating microglia may help reduce the imbalance between neuroprotection and neurotoxicity for neurodegenerative diseases.... Read More...
Huntington’s Disease Starts in Childhood
Researchers say the Huntingtin gene affects brain development from an early age, even though most patients do not develop Huntington's disease until later life.... Read More...
System that Could Reduce Neurodegeneration in Huntington’s Discovered
Researchers have identified a mechanism that may reduce the toxic aggregation of the huntingtin protein. The findings could lead to new treatment options for Huntington's patients.... Read More...
Important New Piece in Huntington’s Disease Puzzle Identified
Researchers have identified a reduced exchange of glutamine between astrocytes and neurons in a new Huntington's disease study.... Read More...
How the Brain Orchestrates Movement
Researchers shed light on what happens to specific neurons when neurodegenerative diseases impact movement. The findings could help in the development of new treatments for Parkinson's and Huntington's disease.... Read More...
Link Between Huntington’s Disease and Rheumatoid Arthritis Discovered
Researchers have identified a genetic overlap between rheumatoid arthritis and Huntington's disease. The findings could open the door to developing new therapeutic targets and medications to combat both conditions.... Read More...
Excess of Mitochondrial Iron Linked to Huntington’s Disease
Researchers have identified an over accumulation of iron in the mitochondria of mice genetically engineered to have Huntington's disease. ... Read More...
Watching Brain Cells Interact in Real Time
Researchers have developed a new method that allows them to see how astrocytes influence neural communication in real time.... Read More...