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high fat diet

·January 9, 2025·4 min read

High-Fat Diets in Adolescence Linked to Adult Impulsivity

Adolescent rats fed a high-fat diet displayed increased impulsivity and altered decision-making as adults. These "cheesecake rats" were quicker to act on visual cues (indicative of impulsivity) but showed more conservative choices in gambling tasks, opting for smaller, safer rewards.

Featured Neuroscience Psychology

·June 17, 2024·5 min read

Junk Food Fuels Anxiety

A high-fat diet can disrupt gut bacteria, alter behavior, and influence brain chemicals in ways that increase anxiety. The study found that rats fed a high-fat diet showed less diversity in gut bacteria and higher expression of genes associated with stress and anxiety. This suggests that unhealthy eating habits may not only lead to weight gain but also negatively impact mental health.

Featured Genetics Neurology Neuroscience

·April 29, 2024·4 min read

High-Fat Diet Linked to Alzheimer’s Through Molecular Changes

A new study uncovered how diets high in saturated fats contribute to the development of Alzheimer’s disease by affecting crucial molecular markers in the brain and blood. The research utilized mouse models to investigate the impact of such diets on the expression of miRNAs related to insulin regulation, revealing significant metabolic deterioration and brain inflammation.

Featured Genetics Neuroscience

·January 3, 2024·6 min read

High-Fat Diets Impact Health, Immunity, and COVID-19 Risk

A new study highlights the effects of high-fat diets on genes associated with obesity, colon cancer, immune function, brain health, and potentially COVID-19 risk. Researchers fed mice three different high-fat diets and observed changes in gene expression, gut bacteria, and susceptibility to infectious diseases.

Featured Neuroscience

·April 5, 2023·3 min read

How to Prevent a High-Fat Diet From Throwing Metabolism Out of Whack

Eliminating SAPS3 from the genome of mice allowed the AMPK protein complex to activate and maintain normal energy balance, even with high-fat meals. This discovery could pave the way for developing a new approach to metabolic disorders such as obesity, diabetes, and fatty liver disease.

Featured Neuroscience

·January 26, 2023·4 min read

Why a High-Fat Diet Could Reduce the Brain’s Ability to Regulate Food Intake

Study reports in the short term, astrocytes regulate caloric intake by controlling the signaling pathway between the gut and brain. Eating high-fat or high-calorie diets disrupts this pathway.

Featured Neuroscience Open Neuroscience Articles

·January 17, 2023·3 min read

High Fat Diet Activates Early Inflammation in Mouse Brains, Supports Link to Neurological Disease

High-fat diets promote early inflammatory responses in the brain via an immune pathway associated with diabetes and neurodegenerative diseases. The findings suggest a link between metabolic dysfunction and cognitive impairment.

Featured Neurology Neuroscience Open Neuroscience Articles

·November 14, 2022·5 min read

High-Fat Diet Can Provoke Pain Sensitivity Without Obesity or Diabetes

High-fat diets induce hyperalgesic priming, a neurological change that represents the transition from acute to chronic pain, and allodynia or pain resulting from stimuli that do not normally provoke pain.

Featured Neuroscience Psychology

·July 8, 2022·4 min read

Long Term High-Fat Diet Expands Waistline and Shrinks Brain

Mice fed a high-fat diet for 30 weeks were considerably more likely to develop diabetes, face cognitive impairments, and develop depression and anxiety. The mice with diet-induced cognitive impairment were also more likely to gain weight excessively due to poor metabolism caused by the brain changes.

Featured Neuroscience Psychology

·April 27, 2020·2 min read

High-fat diet consequences include mental fatigue

Rats fed on a high-fat diet were more mentally exhausted following a novel object recognition test than those fed a healthier diet. Findings suggest high-fat diets not only contribute to obesity, but they can also have an impact on mental fatigue and cognitive abilities.

Brain Cancer Featured Neurology Neuroscience Open Neuroscience Articles

·December 30, 2019·4 min read

Combining neurologic and blood pressure drugs reduces breast tumor development

Combining medications used to treat neurological disorders, such as epilepsy and migraines, with blood pressure medications reversed some aspects of breast cancer in mice at high risk of developing the disease due to the high-fat diets fed to their mothers during pregnancy.

Featured Neurology Neuroscience

·December 26, 2019·3 min read

High fat diet impairs new neuron creation in female mice

Female mice exposed to a high-fat diet have limited hippocampal neurogenesis. The findings may explain why women are at higher risk of developing dementia than men.