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Featured Genetics Neurology Neuroscience

·November 5, 2025·6 min read

3D Brain Map Reveals How Inflammation Reawakens Developmental Genes

Researchers have developed the most detailed molecular map yet of how the brain develops and reacts to inflammation, revealing that disease processes can “reawaken” genes from early life. Using a new spatial tri-omics technique, the team tracked how gene activity, epigenetic changes, and protein production interact in specific brain regions.

Featured Neuroscience

·November 5, 2025·7 min read

AI Creates the Most Detailed 3D Map of the Human Brain Ever Made

A new AI-powered atlas called NextBrain allows researchers to visualize the human brain in unprecedented detail, down to hundreds of tiny subregions previously invisible on MRI scans. Built from 10,000 microscopic slices of post-mortem brains and aligned with AI, the atlas precisely maps 333 brain regions in 3D.

Featured Genetics Neuroscience

·November 4, 2025·7 min read

AI Maps the Brain’s Hidden Bridge, Revealing Genetic Links to Mental Health

For the first time, scientists have mapped the genetic architecture of the brain’s communication bridge—the corpus callosum—using AI and MRI data from over 50,000 people. The study uncovered dozens of genes that shape this vital structure’s size and thickness, many active during prenatal development when the brain’s wiring is established.

Featured Genetics Neurology Neuroscience

·November 4, 2025·6 min read

BrainSTEM Atlas Maps Every Cell of the Developing Human Brain

Scientists have built one of the most comprehensive single-cell maps of the developing human brain. The new BrainSTEM framework analyzed nearly 680,000 fetal brain cells to chart their growth and interactions, offering a detailed reference for studying neuron development.

Featured Genetics Neurology Neuroscience

·November 3, 2025·5 min read

Antioxidant Defense System in the Brain Discovered

A new study identifies biliverdin reductase A (BVRA) as a crucial enzyme defending neurons from oxidative stress, acting independently of its traditional role in bilirubin production. Using genetically modified mice, researchers found that BVRA binds directly to NRF2, a master regulator of antioxidant defense, ensuring the activation of protective genes that maintain cellular health.

This shows two hearts and melatonin pills.

Featured Neurology Neuroscience

·November 3, 2025·9 min read

Long-Term Melatonin Use Linked to Higher Heart Failure Risk

A large-scale analysis of more than 130,000 adults with chronic insomnia found that long-term melatonin use—defined as one year or more—was associated with a striking increase in heart failure, hospitalization, and mortality risk. Using global health records, researchers found that melatonin users had about 90% higher odds of developing heart failure and were nearly twice as likely to die from any cause within five years.

This shows a brain on a pillow and food.

Featured Neuroscience

·November 3, 2025·4 min read

Losing Sleep Might Make You Hungrier and Sleepier Later

New research using fruit flies reveals that sleep loss can trigger both increased eating and sleeping—if the deprivation leads to energy depletion. Flies that lost energy while sleep-deprived compensated with extra rest and food intake, while those deprived without losing energy showed no such rebound.

This shows a woman sitting in a dark room.

Featured Neuroscience Psychology

·November 2, 2025·4 min read

Don’t Ignore the Winter Blues, It Could Be Seasonal Depression

As daylight fades, many experience fatigue or low mood—but for millions, these symptoms signal seasonal affective disorder (SAD), a serious form of depression. Reduced sunlight disrupts serotonin, melatonin, and the body’s circadian rhythm, leading to feelings of hopelessness, loss of interest, and sleep or appetite changes.

Featured Neuroscience Psychology

·October 30, 2025·6 min read

Common Antidepressant Eases Core Symptoms Within Two Weeks

A new analysis of the PANDA clinical trial reveals that sertraline, one of the most prescribed antidepressants, improves key emotional symptoms of depression—such as sadness, self-loathing, and suicidal thoughts—within just two weeks of treatment. Using network analysis to assess individual symptoms, researchers found that the drug also eased anxiety early on, while somatic effects like fatigue and low libido appeared but later stabilized.

This shows a child surrounded by bacteria.

Featured Neuroscience Psychology

·October 30, 2025·6 min read

Toddler Gut Bacteria Linked to Childhood Anxiety and Depression

A new study suggests that a child’s gut microbiome at age 2 may influence their emotional health years later. Researchers found that higher levels of bacteria from the Clostridiales order and Lachnospiraceae family were linked to stronger connectivity across emotion-related brain networks and a higher risk of anxiety and depression symptoms by age 7½.

This shows a cell phone, neurons and a sensor.

Featured Genetics Neuroscience Psychology

·October 29, 2025·8 min read

$2 Saliva Test Could Help Detect Depression and Schizophrenia

Scientists have developed a portable biosensor that can detect levels of BDNF, a protein linked to mental health conditions such as depression, schizophrenia, and bipolar disorder. The flexible, low-cost device analyzes a drop of saliva in under three minutes, offering a fast, affordable, and noninvasive diagnostic tool.

Brain Cancer Featured Neurology Neuroscience

·October 29, 2025·6 min read

How Chemotherapy Triggers Nerve Damage, and How to Stop It

A new study reveals that chemotherapy-induced nerve pain arises from a stress response in immune cells that triggers inflammation and neurotoxicity. Researchers found that activating a cellular stress sensor called IRE1α causes nerve damage and pain during chemotherapy, but blocking it prevents both in mice.

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Health

3D Brain Map Reveals How Inflammation Reawakens Developmental Genes

AI Creates the Most Detailed 3D Map of the Human Brain Ever Made

AI Maps the Brain’s Hidden Bridge, Revealing Genetic Links to Mental Health

BrainSTEM Atlas Maps Every Cell of the Developing Human Brain

Antioxidant Defense System in the Brain Discovered

Long-Term Melatonin Use Linked to Higher Heart Failure Risk

Losing Sleep Might Make You Hungrier and Sleepier Later

Don’t Ignore the Winter Blues, It Could Be Seasonal Depression

Common Antidepressant Eases Core Symptoms Within Two Weeks

Toddler Gut Bacteria Linked to Childhood Anxiety and Depression

$2 Saliva Test Could Help Detect Depression and Schizophrenia

How Chemotherapy Triggers Nerve Damage, and How to Stop It

Touching Without Contact: We Physically Sense Objects Before Feeling Them

Nano Tech Helps CBD Quiet Pain at the Source

Adaptive Music Tech Makes Workouts More Fun, Helps People Stay Active

New Therapy Reshapes Images That Fuel Psychosis

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