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Health

·August 6, 2012·8 min read

Brain Signal IDs Responders to Fast-Acting Antidepressants

Scientists have discovered a biological marker that may help to identify which depressed patients will respond to an experimental, rapid-acting antidepressant like ketamine. The brain signal, detectable by noninvasive imaging, also holds clues to the agent's underlying mechanism, which are vital for drug development, say NIH researchers.

Featured Genetics Neurology

·August 2, 2012·3 min read

Researchers Find Genetic Cause for Body Tremors

Scientists knew that mutations in the FUS gene (Fused in Sarcoma) cause amyotrophic lateral sclerosis (ALS), a disease of the nerve cells in the brain and spinal cord that control voluntary muscle movement. The researchers were successful in identifying mutations in this gene that cause Essential Tremor, and proved that the disease mechanisms for ET and ALS FUS mutations are different.

Brain Cancer Featured Genetics Neurology

·August 1, 2012·3 min read

Researchers Discover Gene that Permanently Stops Cancer Cell Proliferation

Researchers discovered a mutant form of Chk1 gene that when expressed in cancer cells, permanently stopped their proliferation and caused cell death without the addition of any chemotherapeutic drugs. This study illustrates an unprecedented finding, that artificially activating Chk1 alone is sufficient to kill cancer cells.

Featured Neurology

·August 1, 2012·2 min read

Artificial Butter Flavoring Ingredient Linked to Key Alzheimer’s Disease Process

A new study raises concern about chronic exposure of workers in industry to a food flavoring ingredient used to produce the distinctive buttery flavor and aroma of microwave popcorn, margarines, snack foods, candy, baked goods, pet foods and other products. It found evidence that the ingredient, diacetyl (DA), intensifies the damaging effects of an abnormal brain protein linked to Alzheimer’s disease.

A cup of coffee is shown with the froth in the shape of a brain.

Featured Neurology

·August 1, 2012·2 min read

Caffeine May Ease Parkinson’s Symptoms

Caffeine, which is widely consumed around the world in coffee, tea and soft drinks, may help control movement in people suffering from Parkinson's.

Featured Genetics Neuroscience

·July 31, 2012·4 min read

Protein Involved in DNA Replication, Centrosome Regulation Linked to Dwarfism, Small Brain Size

Research just published by scientists at Cold Spring Harbor Laboratory (CSHL) links gene mutations found in some patients with Meier-Gorlin syndrome (MGS) with specific cellular dysfunctions that are thought to give rise to a particularly extreme version of dwarfism, small brain size, and other manifestations of abnormal growth which generally characterize that rare condition.

Featured Neurology Psychology

·July 30, 2012·2 min read

Brain Development is Delayed in Attention-Deficit/Hyperactivity Disorder

Researchers found that development of the cortical surface is delayed in frontal brain regions in children with ADHD. The typically developing children attained 50% peak area in the right prefrontal cortex at a mean age of 12.7 years, whereas the ADHD children didn’t reach this peak until 14.6 years of age.

Brain Cancer Featured Neurology

·July 26, 2012·5 min read

Study Pinpoints a Genetic Cause of Most Lethal Brain Tumor and May Lead to New Treatment

Researchers discovered that some cases of glioblastoma, the most common and aggressive form of primary brain cancer, are caused by the fusion of two adjacent genes. The study also found that drugs that target the protein produced by this genetic aberration can dramatically slow the growth of glioblastomas in mice.

Featured Neurology Neuroscience

·July 25, 2012·4 min read

Chemical Makes Blind Mice See

A team of University of California, Berkeley, scientists in collaboration with researchers at the University of Munich and University of Washington, in Seattle, has discovered a chemical that temporarily restores some vision to blind mice, and is working on an improved compound that may someday allow people with degenerative blindness to see again.

Brain Cancer Featured Neurology

·July 24, 2012·3 min read

New Probe Provides Vital Assist in Brain Cancer Surgery

A new probe developed uses an innovative fluorescence-reading technology to help brain surgeons distinguish cancerous tissue from normal tissue. The probe tool, now already in use at the Cancer Center for brain surgery, may one day be used for surgeries for a variety of cancers.

Neurology Neuroscience Business

·July 19, 2012·2 min read

Anti-Tau Drug Improves Cognition, Decreases Tau Tangles in Alzheimer’s Disease Models

Penn Medicine research presented today at the 2012 Alzheimer's Association International Conference shows that an anti-tau treatment called epithilone D (EpoD) was effective in preventing and intervening the progress of Alzheimer's disease in animal models, improving neuron function and cognition, as well as decreasing tau pathology.

Featured Genetics Neurology Neuroscience Business

·July 17, 2012·3 min read

Experimental Drug May Extend Therapeutic Window for Stroke

An experimental drug that reduces brain damage and improves motor skills among stroke-afflicted rodents when given with federally approved clot-busting therapy has been created.