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GPCRs

This shows a model of the melotonin receptors

·April 24, 2019·7 min read

A good night’s sleep may be in sight: New 3D models of melatonin receptors shed light on sleep disorders

Researchers have created new 3D maps of two melatonin receptors. The models can be used to help develop new treatments that not only improve sleep, but may also treat a variety of other conditions from diabetes to cancer.

Image shows a model of the CB1 receptor.

Featured Neuroscience

·November 16, 2016·4 min read

Highest Resolution Model of Brain Receptor Behind Marijuana’s High Created

Researchers have created the most detailed 3D structure to date of the brain receptor that binds and responds to the root of the marijuana high.

Featured Neuroscience

·May 26, 2016·4 min read

Odor Alternative

Researchers have uncovered a new and different way some odors are sensed in the 'olfactory necklace'.

Image shows researchers looking into a microscope.

Featured Neuroscience

·April 8, 2016·3 min read

A Novel Optogenetic Tool

Researchers use optogenetics to successfully switch specific G-protein coupled signalling pathways on and off.

Featured Neuroscience

·November 10, 2015·4 min read

Sniffing Out Information on Dopamine Receptor Signaling

Researchers report arginine methylation regulates dopamine signaling in human cells.

Illustration of amyloid beta attacking a cell.

Featured Neurology

·October 14, 2015·2 min read

A New Target for Alzheimer’s Disease Treatment

Researchers discovered the GPR3 protein could play an important role in reducing the generation of amyloid beta and in alleviating cognitive deficits in Alzheimer's disease.

This is a sensory neuron in lung tissue.

Featured Neuroscience

·April 16, 2015·5 min read

Sensory Neuron Subtyes Control Different Respiratory Functions

Researchers deconstruct the vagus nerve.

This is a drawing of a brain with cog wheels inside it.

Featured Neuroscience

·March 6, 2014·5 min read

Scientists Create Detailed Picture of Membrane Protein Linked to Brain Disorders

Researchers gain a better understanding of the mGlu1 receptor which they believe to be a viable target for future medications to treat a number of brain disorders.

The image shows the mu opioid receptor. The caption best describes the image.

Featured Neuroscience Open Neuroscience Articles

·June 14, 2013·5 min read

Researchers Design Variant of Main Painkiller Receptor

Researchers have developed a variant of the Mu opioid receptor which has several advantages for experimentation The variant can be grown in large quantities and is water soluble, allowing for experiments and applications which have previously been challenging.

The image shows the structure of serotonin. The caption best describes the image.

Featured Neuroscience

·March 21, 2013·7 min read

Study Reveals How Serotonin Receptors Can Shape Drug Effects from LSD to Migraine Medication

Researchers analyze the atomic structure of two types of human serotonin receptors. Their findings could explain why some drugs, which interact with these receptors, occasionally have harmful effects.