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glymphatic system

·September 7, 2023·4 min read

Glymphatic System Key to Parkinson’s Protein Spread and Aggregation

Researchers shed light on the puzzle of Parkinson’s disease progression. They discovered that a mutated version of the α-synuclein protein moves through the brain's lymphatic system, known as the glymphatic system, before aggregating.

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·May 16, 2023·5 min read

Ultrasound Technique Boosts Brain’s Waste Disposal, Aiding Disease Research

Researchers developed a noninvasive, nonpharmaceutical method to enhance the glymphatic transport in the brain. The technique, known as focused ultrasound combined with circulating microbubbles (FUSMB), amplifies the effects of ultrasound waves on blood vessels, facilitating the removal of metabolic waste and distribution of nutrients.

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·December 19, 2022·6 min read

How the Human Brain Drains Fluid

A new study of the recently discovered brain's lymphatic system may shed new light on various brain diseases and how fluid drainage may play a role.

This shows a 3d map of the brain's drainage system

Featured Neuroscience

·August 2, 2022·3 min read

The Brain’s Drainage System in 3D

The CSF drainage pathways are similar between mice and humans, researchers discovered.

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·May 27, 2022·4 min read

On Your Back, Side, or Face-Down? How We Sleep May Trigger or Protect Our Brain From Diseases Like ALS

A new mouse study reveals our sleep position may influence the glymphatic system and could increase the risk of developing ALS or other neurodegenerative diseases.

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·March 8, 2022·3 min read

Waste Management in the Brain May Shed Light on Dementia

When cerebral amyloid angiopathy is present, the brain diverts most of the waste-removing fluid away from the glymphatic system.

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·October 27, 2021·4 min read

Initiative to Improve Sleep and Clearance of the Brain

A new study aims to assess the usefulness of a new technology that could speed up and enhance the clearing of metabolic waste via the glymphatic system as a person sleeps.

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·March 12, 2021·4 min read

The Role of Sleep in Healing Traumatic Brain Injuries

In veterans who suffered a TBI, lack of sleep was associated with enlarged perivascular spaces and an increase in post-concussive symptoms.

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·September 3, 2020·4 min read

Researchers Probe Soldier Sleep Deprivation Effects

Study reveals how sleep deprivation can greatly affect soldiers on the battlefield.

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·September 2, 2020·5 min read

Circadian Rhythms Help Guide Waste From Brain

During wakeful periods, the glymphatic system diverts cerebrospinal fluid to lymph nodes in the neck. The CSF may act as a "fluid clock" that helps initiate the body's infection-fighting capabilities during the day. Astrocytes in the suprachiasmatic nucleus may serve to control CSF through the central nervous system. Communication between astrocytes in different brain regions may optimize the glymphatic system's function as we sleep.

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·January 30, 2020·4 min read

Brain drowns in its own fluid after a stroke

Following a stroke, dysfunction in the glymphatic system causes cerebrospinal fluid to flood the brain, drowning neurons, and triggering cerebral edema.