Melanocyte stem cells from human hair follicles that carry CD34 have the ability to turn into glial cells. The CD34+ stem cells can regenerate myelin, both on neurons and in mouse models with a genetic defect that prevents the formation of healthy myelin sheaths. The findings could have positive implications for the treatment of demyelinating diseases, such as Multiple Sclerosis.
Yale researchers successfully restored cellular activity and circulation to a pig's brain, four hours after its death. The research challenges the assumption about both timing and the irreversible nature of the cessation of some brain functions following death.
Axolotl salamander genes that allow the neural tube and nerve fibers to regenerate after spinal cord damage have been identified. These genes are also found in humans, but are activated differently.
Researchers describe their findings about how the Foxg1 gene is involved in the development and differentiation of neurons and glial cells from stem cells.
Researchers have identified a small set of molecules that can convert glial cells into new neurons. The finding could help develop new treatments for Alzheimer's disease and brain injuries.
A new study reveals a defective version of astrocytes may be linked to the build up of alpha synuclein and could spur Parkinson's disease. The findings show the important role glial cells play in Parkinson's and offers insights into new targets for therapies to fight the neurodegenerative disease.
A new study reports some people with schizophrenia have increased numbers of immune cells in their brains. Researchers say the immune cells may be producing inflammatory signals in those with the condition.
Researchers say a novel enzyme treatment may reduce inflammation and scarring that prevents neural regeneration in spinal cord injury.