Glial cells coordinate immune responses in the gut following infection. Researchers report glial cells could be targets for therapeutics to treat inflammatory bowel disorders.
COVID-19 may not directly infect the brain, but the virus is still capable of causing significant neurological damage, a new study reports. Researchers say the neurological changes seen as a result of coronavirus infection are likely related to inflammation triggered by viral infection in different parts of the body or the brain's blood vessels.
Axon regeneration and dramatic improvements in functional recovery occurred when lactate was applied to damaged neural tissue. Treatment with lactate also significantly improved locomotion and restored some walking capability in mouse models of SCI.
Glial cells not only control the speed of nerve conduction, but they also influence the precision of signal transduction.
Researchers directly measured oxygen levels in an intact brain and correlated it with neural activity. During normal activity, only 50% of oxygen is used for neural activity, the remaining 50% is required for glial cells and maintaining the metabolic rate of other nerve cells.
Astrocytes are not uniform, as previously believed, but take distinct molecular forms depending on their location in the cerebral cortex. Astrocytes also organize in layers in similar ways to neurons.
Study looks at the evolutionary development of the human brain.
Inflammation caused by opioid use to both the brain and gut may exacerbate symptoms of negative emotions associated with withdrawal. Targeting the inflammation could help alleviate the negative experiences of opioid withdrawal and prevent dependence.