New research in cloned pigs with a mutation of the SORL1 sheds light on Alzheimer's development. The findings could pave the way for new treatments for the neurodegenerative disorder.
Using CRISPR gene editing, researchers were able to control microglia and reverse their toxic state associated with Alzheimer's disease, and put them back on track.
Gene editing could be a potential new treatment for anxiety and alcohol use disorder in adults who indulged in binge drinking as adolescence.
Using gene editing to disrupt a gene in the thalamus that codes for a protein that binds to GABA boosted the activity of delta waves and promoted deep sleep in mouse models.
Researchers successfully transplanted genetically modified, clinical-grade pig kidneys into a brain-dead human, replacing their native kidneys. The results demonstrate how xenotransplantation could help address organ shortages.
Gene editing may provide hope for the treatment of Fragile X, the leading genetic cause of autism.
The dSlo2 channel appears to play a role in suppressing hyperactivity in the brain that causes epileptic seizures.
Mouse study identifies specific neurons and a signaling pathway to regions of the hindbrain that mediate sexual reproductive activity and physical activity that appear to influence activity behaviors during ovulation. The findings may provide valuable insights into how estrogen loss during menopause disrupts this activity.
People are less averse to the use of CRISPR gene editing in agriculture if the technology is used to promote disease resistance in animals. However, people tend to dislike the use of CRISPR when it comes to new breeding methods.
CRISPR gene-editing technology allowed researchers to pinpoint specific neurons and mechanisms related to the effects of oxidative stress in the brain.
PLCG2-P522R, a genetic variant that protects against Alzheimer's disease, enhances key functions of immune cells.
Study reveals how a protein that transports essential amino acids across the placenta plays a role in fetal development. Deficiencies of the SNAT4 protein may result in developmental abnormalities and a higher risk of miscarriage.
