People are less averse to the use of CRISPR gene editing in agriculture if the technology is used to promote disease resistance in animals. However, people tend to dislike the use of CRISPR when it comes to new breeding methods.
Study reveals how a protein that transports essential amino acids across the placenta plays a role in fetal development. Deficiencies of the SNAT4 protein may result in developmental abnormalities and a higher risk of miscarriage.
Using CRISPR to alter the expression of four schizophrenia implicated genes which harbor expression quantitative trait loci, researchers were able to mirror gene expression changes seen in postmortem brains of those suffering from three mental health disorders.
Using CRISPR gene editing, researchers introduce the SHANK3 gene variant into macaque monkeys. SHANK3 has previously been linked to autism in humans. The monkeys with the SHANK3 mutations exhibited behavioral traits and brain activity patterns similar to those seen in humans on the autism spectrum, Researchers hope the new model will facilitate new avenues of research for ASD.
The chemical probe CDr20 can label microglia in living cells, researchers report.
Using CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.
By optimizing neurons with CRISPR gene editing technology, researchers will have new ways to study genetic influences on brain health and disease, a new study reports.
Researchers have identified a specific mechanism involved in how females inherit traits. The findings could help reduce susceptibility to Fragile X and Rett syndrome, the researchers report.