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GCase

·January 11, 2023·3 min read

Cough Medicine Could Be Used in New Treatment for Parkinson’s Disease

Ambroxol, a common medicine used to treat respiratory illnesses shows promise as a treatment to slow the progression of Parkinson's disease. Researchers report ambroxol increases the level of GCase, a protein that allows cells to remove waste proteins including alpha synuclein.

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·February 16, 2020·4 min read

Cough syrup drug being trialed as Parkinson’s treatment

Ambroxol, a medication approved to treat coughs, may slow the progression of Parkinson's disease. The medication is able to effectively cross the blood-brain barrier and increases levels of GCase in patients' brains. Ambroxol also appears to reduce Parkinson's-related alpha-synuclein levels.

Featured Neurology Open Neuroscience Articles

·April 29, 2018·4 min read

Lipid Accumulation in Brain May Be an Early Sign of Parkinson’s

Researchers report the accumulation of glycosphingolipids in the substantia nigra appears to be elevated in Parkinson's disease patients. The finding could be used as a biomarker for helping diagnose Parkinson's before symptoms of the disease set in.

Featured Neurology

·September 8, 2017·4 min read

Interrupting Parkinson’s Disease

A new study reports antioxidant intervention during early stages of Parkinson's disease may help slow its progression.

This image shows Sir William Richard Gowers' 1886 illustration which was part of his documentation of Parkinson's disease.

Featured Neurology

·October 8, 2014·3 min read

Parkinson’s Progression Slowed by Drug Being Evaluated for Gaucher Disease

A drug which is being evaluated for the treatment of Gaucher disease has been shown to help slow the progression of Parkinson's disease in mice, a new study reports.