GABA Research Articles - Neuroscience News

Researchers identify new hunger pathway in the brain

Neuroscience NewsJune 24, 2019

Newly identified network in the hypothalamus alters feeding behaviors on a shorter timescale. The pathway affects food intake and body weight by releasing GABA, which may occur due to the detection, and not the consumption of food.... Read More...

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Research confirms gut-brain connection in autism

Neuroscience NewsMay 30, 2019

Genetic mutations, which occur in both the brain and gut, could be a main cause of autism. Using mouse models of ASD, researchers discovered the neuroligin-3 R451C mutation affects neural communication in the brain and causes dysfunction in the gut. The findings strengthen the gut-brain hypothesis of autism.... Read More...

AutismFeaturedGeneticsNeuroscienceOpen Neuroscience Articles7 min read

Targeting key gene could help lead to down syndrome treatment

Neuroscience NewsMay 23, 2019

Using stem cells from candidates with Down syndrome to create an organoid, and employing mouse models, researchers pinpoint a gene linked to memory impairments and cognitive problems in Down syndrome. Inhibiting the OLIG2 gene leads to cognitive and memory improvements in mouse models of Down. Researchers hope their findings lead to an in utero treatment that targets the gene and helps reverse abnormal brain development. ... Read More...

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This shows the lead research looking after a baby in a neonatal ward

Placental function linked to brain injuries associated with autism

Neuroscience NewsApril 27, 2019

Disruptions in the supply of allopregnanolone, a hormone created by the placenta late in pregnancy, to the developing fetus can leave children more vulnerable to brain injuries associated with ASD. Losing the supply of ALLO alters cerebellar development, an area of the brain critical for motor coordination and social cognition, impacting the post-birth development of cerebellar white matter. An experimental model revealed deficient cerebellar white matter resulted in social impairments and an increase in repetitive behaviors, two hallmark features associated with autism. ... Read More...

AutismFeaturedNeuroscience3 min read

This shows a brain with bobbles and lines forming networks

Brain’s support network may play key role in attention deficit, hyperactivity behaviors: Rodent study

Neuroscience NewsApril 26, 2019

Astrocytes can alter neurons to drive behaviors associated with ADHD. Researchers believe astrocytes may be used to develop targeted treatments for behavioral deficits associated with a range of mental illnesses.... Read More...

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This shows AAN activation in the supraoptic nucleus

General anesthesia hijacks sleep circuitry to knock you out

Neuroscience NewsApril 18, 2019

Study reveals anesthesia activated neurons have been discovered in the hypothalamus. Activation of AANs promotes slow-wave sleep, extending the effects of anesthesia, while inhibition of AANs shortens the duration of general anesthetics and disrupts natural sleep.... Read More...

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This shows the chemical structure of oxytocin

Oxytocin could help treat alcohol use disorder: Rat Study

Neuroscience NewsApril 16, 2019

Administering oxytocin blocks the enhanced motivation for drinking alcohol that fuels alcohol use disorder by blocking GABA signaling in the central nucleus of the amygdala.... Read More...

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Protein pileup affects social behaviors through altered brain signaling

Neuroscience NewsApril 10, 2019

Study implicates disrupted autophagy and protein aggregation in the pathogenesis of autism schizophrenia and social behavior deficits in other disorders.... Read More...

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Researchers Describe First Model of Mitochondrial Epilepsy

Neuroscience NewsFebruary 15, 2019

Researchers have developed a new model of mitochondrial epilepsy which captures specific features observed in patients. The new model may help provide better therapies and treatments for the condition.... Read More...

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New Molecules Reverse Memory Loss Linked to Depression and Aging

Neuroscience NewsFebruary 14, 2019

Researchers have developed new therapeutic molecules that appear to assist in reversing memory loss associated with depression and aging.... Read More...

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