GABA

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GABA

·June 17, 2020

Scientists gain detailed images of how a protein that calms brain activity works

Cryo-electron microscopy captures detailed snapshots of the GABAB receptor protein contorts as it interacts with GABA. Read More

Featured Neurology Neuroscience pain

·May 18, 2020

Scientists find brain center that ‘profoundly’ shuts down pain

Researchers identified a distinct population of GABAergic neurons activated by general anesthetic in the central amygdala of mice. The findings point to central amygdala GABAergic neurons as a potential therapeutic target to alleviate chronic pain. Read More

Featured Neuroscience Open Neuroscience Articles

·May 4, 2020

Exercise boosts motor skill learning via changes in brain’s transmitters

Neurons in the caudal pedunculopontine nucleus, an area of the brain that regulates motor coordination, switch neurotransmitters from acetylcholine to GABA as a result of exercise. The switch appears to provide feedback control that regulates motor coordination and skill learning. Read More

Featured Neurology Neuroscience Psychology

·April 2, 2020

How T. gondii infection causes seizures, and psychiatric illness for some

Study shows how Toxoplasma parasitic infections promote the loss of inhibitory signaling in the brain by altering the behavior of microglia. Read More

This shows the firing patterns of the neurons

Featured Neuroscience

·March 3, 2020

How our brains create breathing rhythm is unique to every breath

Each breath begins with hundreds of individual neurons haphazardly firing at low levels, then quickly synchronizing. The synchronization prompts activity that signals diaphragm and chest muscles to contract, causing expansion and inhalation. As the signal subsides, exhalation occurs. Read More

auditory neuroscience Autism Featured Genetics Neuroscience visual neuroscience

·March 2, 2020

Why those on the autism spectrum are often hypersensitive to light and noise

Mice lacking the autism-associated SHANK3 gene were more sensitive to sensation, including touch. The mice also had overactive excitatory neurons in the somatosensory cortex, which may account for sensory hypersensitivity. Read More

Electrophysiology Featured Neuroscience

·February 25, 2020

Shining new light on the actions of key neurotransmitter in the brain

GABA can selectively regulate the excitability of neurons. Read More

Autism Featured Neuroscience Open Neuroscience Articles

·January 27, 2020

Prescription drug improves symptoms of autism by targeting brain’s chemical messengers

A drug commonly prescribed for edema improves the symptoms for young children on the autism spectrum with no significant side effects. The drug, bumetanide, decreases the ratio of GABA to glutamate in the brain. Read More

Featured Neuroscience Psychology

·January 1, 2020

New Year’s anxiety hangover? Here’s what’s happening in your brain

Hangxiety, the feeling of waking up with anxiety the morning after heavy drinking, is a common symptom associated with a hangover. Researchers explain how a heavy night's drinking alters neurochemistry, leaving some of us prone to waking with anxiety. Read More

This shows the location of the ventral pallidum in the brain

Featured Neuroscience

·December 31, 2019

How the brain balances pleasure and pain

Different classes of neurons in the ventral pallidum control positive and negative motivations, sending opposing signals along a shared motivation-processing circuit. Read More

Featured Neuroscience

·November 16, 2019

Your brain on sugar: What the science actually says

From reducing memory capability to increasing the risk of diabetes and obesity, researchers investigate how sugar affects the brain and body. Read More

This shows a male and female head surrounded by different colors

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·September 3, 2019

The neurobiological mechanisms behind schizophrenia may depend on gender

Schizophrenia is linked to alterations in pathways associated with glycosaminoglycan, neurotransmitter metabolism, and GABAergic synapses. A large percentage of genes related to schizophrenia are expressed differently between males and females. The results imply the mechanisms involved in schizophrenia development differ, at least slightly, between males and females. Read More

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