Children have a rapid boost of GABA during visual learning tasks that continue after the training ends. In adults, GABA levels remain consistent. Findings suggest children's brains respond to training in a way that allows the to more quickly and more efficiently stabilize learning.
Researchers characterize a novel neural population within the striatum that appears to be responsible for the interplay between acetylcholine and GABA.
Gene therapy that inhibits targeted nerve cell signals effectively improves symptoms of neuropathic pain without negative side effects in mouse models of spinal cord injury or peripheral nerve damage.
A new investigation into interneuron development sheds light on how disorders associated with neurodevelopment, such as autism and schizophrenia may occur.
A new rodent study uncovers a neural circuit in the brain that appears to govern pain-induced anhedonia. Altering the activity of this circuit restored motivation in pre-clinical models of pain.
Study reports a significant number of people with Parkinson's disease have precise deficits when learning from instructions. Researchers say the problems are associated with differences in brain function.
Researchers have identified a new reward system in the brain. The study found long-range GABA neurons from the ventral tegmental area to the ventral nucleus accumbens shell are engaged in reward and reinforcement behaviors. This GABAergic projection inhibits cholinergic interneurons.