Researchers characterize a novel neural population within the striatum that appears to be responsible for the interplay between acetylcholine and GABA.
Gene therapy that inhibits targeted nerve cell signals effectively improves symptoms of neuropathic pain without negative side effects in mouse models of spinal cord injury or peripheral nerve damage.
A new investigation into interneuron development sheds light on how disorders associated with neurodevelopment, such as autism and schizophrenia may occur.
A new rodent study uncovers a neural circuit in the brain that appears to govern pain-induced anhedonia. Altering the activity of this circuit restored motivation in pre-clinical models of pain.
Study reports a significant number of people with Parkinson's disease have precise deficits when learning from instructions. Researchers say the problems are associated with differences in brain function.
Researchers have identified a new reward system in the brain. The study found long-range GABA neurons from the ventral tegmental area to the ventral nucleus accumbens shell are engaged in reward and reinforcement behaviors. This GABAergic projection inhibits cholinergic interneurons.
The brain regulates both eating for hunger and pleasure through serotonin-producing neurons in the midbrain, but the different types of feeding are wired by independent circuits that do not influence the other type of feeding.
A new study found a person's math ability was linked to levels of GABA and glutamate in the brain. In children, greater math fluency was associated with higher GABA levels in the left intraparietal sulcus, while lower levels of GABA were linked to math ability in adults. The reverse was true for glutamate in both children and adults.