Findings could lead to new treatments for Rett Syndrome and other forms of autism, researchers report.
Researchers have identified a significant role dopamine plays in the development of heroin addiction. The study reports dopamine appears to directly cause drug reinforcement and, when dopamine neurons are silenced, mice are less likely to self administer the drug.
New findings from Max Plank Institute researchers challenges conventional belief about the role of the thalamus in learning. Researchers report the thalamus plays a far more active role in visual processing in the context of learning than previously thought.
Newly identified network in the hypothalamus alters feeding behaviors on a shorter timescale. The pathway affects food intake and body weight by releasing GABA, which may occur due to the detection, and not the consumption of food.
Researchers explain how a molecular amplification system helps a new class of antidepressants alter brain signaling in specific neurons and how this produces the antidepressant effect.
A new study shows the effectiveness of ketamine in treating depression in a mouse model of the disease and also helps bring together two hypotheses for the cause of depression.
Administering oxytocin blocks the enhanced motivation for drinking alcohol that fuels alcohol use disorder by blocking GABA signaling in the central nucleus of the amygdala.
Neuroscience research published in September's Journal of Neuroscience suggests early life stresses may modify the GAD1 gene, which controls the production of GABA. Through their research on rats, researchers were able to note that those who experienced a lack of affection showed an obstruction within the DNA which controls the GAD1 gene. As it is believed that GABA deficits might be apparent within schizophrenic patients, researchers propose that the modification of GAD1 might determine a child's predisposition to mental illness.
Researchers have solves a longstanding mystery relating to perineuronal nets, giving rise to potential new treatments for epilepsy. The study reports the nets modulate electrical impulses in the brain and seizures can occur if perineuronal networks are dissolved.