frontotemporal dementia

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frontotemporal dementia

·September 24, 2022·4 min read

Landmark Study of Biomarker Data May Enable Better Treatment for Early Onset Dementia

Using neuroimaging and fluid biomarkers from those with the familial form of frontotemporal dementia (FTD), researchers developed models of clinical and biomarker dynamics to determine the temporal sequences of biomarkers and clinical changes in f-FTD before disease progression begins.

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Featured Neurology Neuroscience

·August 4, 2022·7 min read

Similarity Between Schizophrenia and Dementia Discovered for the First Time

Study reveals striking similarities in both behaviors and neuroanatomical changes between people with schizophrenia and behavioral-variant frontotemporal dementia.

Featured Neurology Neuroscience

·May 3, 2022·4 min read

Brain Folds Formed During Fetal Stage Could Affect Onset of Dementia

Brain folds that form during fetal development may have an impact on the age at which symptoms of frontotemporal dementia occur.

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Featured Genetics Neurology Neuroscience

·April 23, 2022·5 min read

Unexpected Protein Could Play Role Frontotemporal Dementia

Amyloid fibrils in those with frontotemporal lobar degeneration (FTLD) contain a little-known protein called TMEM106B. Researchers speculate TMEM106B could be found to be the cause of FTLD.

Featured Neurology Neuroscience

·April 7, 2022·4 min read

Brainstem Atrophy Is Linked to Extrapyramidal Symptoms in Frontotemporal Dementia

Patients who suffer from frontotemporal dementia with extrapyramidal symptoms have brainstem atrophy and reduced metabolic activity in specific brain regions compared to those with FTD without extrapyramidal symptoms.

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Featured Neurology Neuroscience

·March 10, 2022·4 min read

Motor Neuron Toxin Associated With ALS Identified

PolyP, an inorganic polyphosphate released by astrocytes in people with ALS and frontotemporal dementia contributes to the signature motor neuron death associated with the disease pathologies.

Featured Neurology Neuroscience

·March 8, 2022·5 min read

Dementia Patients Struggle to Cope With Change Because of Damage to General Intelligence Brain Networks

Damage to the multiple demand network, a brain network associated with general intelligence, causes people with dementia to struggle to adapt to changes in their environment

Featured Genetics Neurology Neuroscience

·February 28, 2022·4 min read

A New Molecular Pathway Shared by Two Neurodegenerative Disorders Discovered

Mislocalization of the TDP-43 protein alters the genetic instructions for UNC13A. The findings provide a potential new therapeutic target for the treatment of ALS and frontotemporal dementia.

Featured Neurology Neuroscience

·July 26, 2021·5 min read

Early Signs of Frontotemporal Dementia Found in Personalized Cerebral Organoids

Researchers recreated the damage seen in frontotemporal dementia in brain organoid models. The study reveals an experimental drug designed to treat Crohn's disease may help prevent neuron death associated with FTD.

Featured Neurology Neuroscience

·July 20, 2021·4 min read

Spinal Fluid Biomarkers Detect Neurodegeneration and Alzheimer’s Disease in Living Patients

Researchers report Alzheimer's disease and other neurodegenerative disorders can be confirmed in living patients by specific biomarkers in cerebrospinal fluid.

Featured Neurology Neuroscience Psychology

·April 12, 2021·5 min read

Profound Loss of Pleasure Related to Early-Onset Dementia

Study links anhedonia, or the loss of pleasure, to the early onset of frontotemporal dementia. Neuroimaging revealed symptoms of anhedonia were marked by atrophy in the frontal and striatal brain areas of those with FTD.

Featured Neurology Neuroscience

·February 17, 2021·3 min read

White Matter Changes in Brain Found in Frontotemporal Dementia

Study reveals those with frontotemporal dementia have greater white matter hyperintensity than those with other forms of dementia. The amount of white matter hyperintensity was associated with the severity of FTD symptoms.

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