LATE, a form of dementia that appears in the oldest-old is often mistaken for Alzheimer's disease, but the brain pathology is very different. The protein TDP-43 appears to play a significant role in the development of LATE. The neurodegenerative disease may progress more gradually than Alzheimer's, but when combined with Alzheimer's disease (a common combination), appears to cause a more rapid decline than either would alone.
Children from lower socioeconomic backgrounds, and whose mothers have lower levels of education, have weaker brain activity in areas of the brain associated with working memory and are more likely to experience attention problems.
Transcranial alternating current brain stimulation (tACS) significantly reduced symptoms in people diagnosed with major depressive disorder in a pilot clinical trial.
A new study reports those with alcohol addiction who also smoke may be at an increased risk of neural damage. The study revealed higher levels of oxidative stress in the hippocampus, and a a decrease in neurotrophic factor in the striatum and frontal cortex in rats exposed to both alcohol and tobacco.
Researchers may have solved one of the great mysteries of neuroscience; namely, why neurons in the temporal lobe are the first to die in Alzheimer's disease, and why dopaminergic neurons are damaged first in Parkinson's.
A new study reveals unique connections within brain networks in children on the autism spectrum. Researchers say, in ASD, the amygdala shows marked differences in connection with the occipital cortex than in typically developing children.
A new study reports the serotonin system is made up of multiple parallel pathways that affect the brain in different, and sometimes opposing, ways.
A family with a rare genetic mutation are helping researchers answer important questions about how the human brain is wired. The family, who share an altered copy of the DCC gene, have less connectivity between areas where dopamine neurons originate and their target sites.