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fibrils

·June 15, 2020·4 min read

New indication of a link between Alzheimer’s and diabetes

A new high-resolution 3D model reveals strong similarities in fibril structures associated with Alzheimer's and type 2 diabetes.

This shows the structure of amyloid beta

Featured Neurology Neuroscience

·May 17, 2019·3 min read

Identifying the molecular structure of one of Alzheimer’s stickier culprits

Researchers map a toxic protein associated with Alzheimer's disease. The study reports that pS8-AB40 acts as the alpha structure in polymorphism and has higher levels of cellular toxicity compared to other fibrils.

Featured Neurology

·July 18, 2016·2 min read

How Proteins in the Brain Build Up Rapidly in Alzheimer’s

Researchers report they have discovered the mechanism that leads to the rapid build up of amyloid plaques in Alzheimer's disease.

Featured Neurology

·March 1, 2016·3 min read

The Evolution of Amyloid Toxicity in Alzheimer’s

Researchers have uncovered structural markers to differentiate between smaller and larger forms of amyloid beta molecules.

The image shows prefoldin protein expression in mice.

Featured Neurology

·July 12, 2013·2 min read

Fighting Alzheimer’s Disease with Protein Origami

Researchers find the human protein prefoldin can reduce neurotoxicity in the clumps of beta-amyloid which collects in the brains of Alzheimer's patients.

Three panels show tangles and Lewy bodies.

Featured Neurology

·July 3, 2013·4 min read

Shape-shifting Disease Proteins May Explain Variable Appearance of Neurodegenerative Diseases

Researchers discover alpha-synuclein proteins can morph into different strains. This can promote misfolding of other disease proteins associated with neurodegenerative diseases.