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EGFR

Brain Cancer Featured Genetics Neuroscience

·January 21, 2023·2 min read

Protein Movement Reveals Brain Tumor’s Weak Spot

In glioblastoma brain cancer, EGFR (HER1) genetic mutations lead to a movement of a large part of the extracellular region of the protein. This activates the intracellular area in a particular way that drives glioblastoma tumor development.

Brain Cancer Featured Neurology Neuroscience Open Neuroscience Articles

·March 23, 2021·4 min read

A New Strategy for Fighting Brain Cancer

Study shows how cholesterol becomes dysregulated in brain cancer cells and reports the gene responsible for the dysregulation could be a potential target to help treat glioblastoma brain cancer.

Brain Cancer Featured Neurology Neuroscience Open Neuroscience Articles

·March 25, 2020·4 min read

Lung cancer therapy may improve outcomes of metastatic brain cancer

Medications commonly used to treat non-small cell lung cancer that has metastasized may have therapeutic benefits for patients with metastatic brain cancers.

Brain Cancer Featured Neurology Neuroscience Open Neuroscience Articles

·January 23, 2020·2 min read

Unexpected connection between gliomas and neurodegenerative diseases

Study finds significant expression of the Alzheimer's related Tau protein in glioma cells, especially in patients with better prognoses.

Brain Cancer Featured Genetics Neurology Neuroscience

·November 21, 2019·5 min read

Non-coding DNA located outside chromosomes may help drive glioblastoma

Extra DNA is critical for maintaining cancer-causing gene activation and supporting the cancer cell's ability to survive.

This shows brain slices with a glioblastoma tumor

Brain Cancer Featured Neurology Neuroscience

·August 8, 2019·5 min read

Adding MS drug to targeted cancer therapy may improve glioblastoma outcomes

Teriflunomide, a drug commonly used to treat multiple sclerosis, shows promise for the treatment of glioblastoma when coupled with targeted cancer therapies.

Brain Cancer Featured Genetics Neurology Neuroscience

·July 19, 2019·6 min read

Study hints at why an aggressive form of brain cancer is hard to treat

Genetics and microenvironment influence the frequency of glioblastoma cells. Researchers provide a new blueprint for glioblastoma, integrating the malignant cell programs, cancer cell plasticity, and modulation by genetic drivers. The findings shed light on why this form of cancer is so hard to treat effectively.

a brain slice from a patient with glioblastoma brain cancer

Brain Cancer Featured Genetics Neurology

·June 4, 2018·5 min read

A Potential Achilles Heel in Brain Cancer

A new study in PNAS reports blocking the expression of MDA-9/Syntenin forces glioma stem cells to lose their ability to induce protective autophagy.

Featured Genetics Neuroscience Open Neuroscience Articles

·December 15, 2017·4 min read

To Sleep or Not to Sleep: The Complex Genetic Network Behind Sleep Duration

NIH researchers have identified a set of genes they believe could explain why some people need more, or less, sleep that others. The findings could help to develop new treatments for a variety of sleep disorders from insomnia to narcolepsy.

Brain Cancer Featured Neurology

·October 10, 2017·5 min read

New Approach to Destroying Deadly Brain Tumors

Researchers at UT Southwestern report medications used to treat arthritis and lung cancer may help in the battle against glioblastoma.

Brain Cancer Featured Neurology

·October 9, 2017·4 min read

Combination Treatment Targeting Glucose in Advanced Brain Cancer Shows Promising Results in Preclinical Study

UCLA researchers report erlotinib, an FDA approved drug, reduces glucose uptake in glioblastoma, effectively cutting off nutrients and energy supply to the tumor.

Image shows a brain scan from a cancer patient.

Brain Cancer Featured Neurology Open Neuroscience Articles

·September 28, 2017·8 min read

Study Splits Incurable Childhood Brain Tumors Into 10 New Diseases

Based on a large scale meta analysis, researchers report striking differences between children's high grade gliomas, so much so that they could be split into 10 different subtypes based on different characteristics. The findings have important implications for developing new and individualized treatments.

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EGFR

Protein Movement Reveals Brain Tumor’s Weak Spot

A New Strategy for Fighting Brain Cancer

Lung cancer therapy may improve outcomes of metastatic brain cancer

Unexpected connection between gliomas and neurodegenerative diseases

Non-coding DNA located outside chromosomes may help drive glioblastoma

Adding MS drug to targeted cancer therapy may improve glioblastoma outcomes

Study hints at why an aggressive form of brain cancer is hard to treat

A Potential Achilles Heel in Brain Cancer

To Sleep or Not to Sleep: The Complex Genetic Network Behind Sleep Duration

New Approach to Destroying Deadly Brain Tumors

Combination Treatment Targeting Glucose in Advanced Brain Cancer Shows Promising Results in Preclinical Study

Study Splits Incurable Childhood Brain Tumors Into 10 New Diseases

Study Revolutionize Restless Legs Syndrome Treatment

Metabolic Pathways Link Cannabis to Psychosis in Teens

Schizophrenia Risks Tied to Psychedelic Use

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