Opioid use disorder affects genes associated with proinflammatory immune molecule encoding and genes associated with remodeling the extracellular matrix, suggesting the connection between neurons may be altered as a result of opioid use. Additionally, those with OUD have higher levels of microglia in the brain.
The stronger the connection between the dorsolateral prefrontal cortex and temporal-parietal junction, the less likely people are to punish others for selfish deeds.
Non-invasive brain stimulation, such as rTMS, helps to reduce smoking frequency in nicotine-dependent people, a new study reports. Stimulating the dorsolateral prefrontal cortex with repetitive transcranial magnetic stimulation significantly reduced smoking frequency.
When we talk to someone from a different socioeconomic background our brain reacts differently than when we address someone with a similar status to our own. Researchers found higher activity in the dorsolateral prefrontal cortex, an area of the brain associated with language and attentional control when people speak with those of different socioeconomic status.
Repetitive transcranial memory stimulation applied to the dorsolateral prefrontal cortex modifies the negative effects of fear memories. The findings could have implications for the treatment of PTSD.
Researchers have identified a hippocampal neural network that activates during stress. Activity in a hippocampal-hypothalamus network predicts greater feelings of stress, while connectivity between the hippocampus and dorsolateral prefrontal cortex predicts less stress.
Researchers identify genetic variations in the prefrontal cortex during different stages of development to assess how psychiatric conditions, such as autism and schizophrenia, may arise in individuals.
Tenacity, a newly developed video game that promotes mindfulness, alters connectivity between the dorsolateral prefrontal cortex and the inferior parietal cortex. These areas of the brain are critical for attention. After playing the game for a short period, participants reported improvements in attention.
Reduced gray matter volume in the insula and dorsolateral prefrontal cortex may represent a genetically conferred predispositional risk factor for alcohol use disorder.