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dorsal root ganglion

This shows a foot radiating red light, symbolizing pain.

Featured Genetics Neurology Neuroscience Pain

·May 13, 2025·7 min read

Century-Old Mystery May Hold the Key to Diabetic Nerve Pain

A little-known cellular structure called the Nageotte nodule—first described over 100 years ago—has been identified as a key feature of diabetic neuropathy in new research. These nodules, made of decayed sensory neurons and support cells, were found in abundance in the sensory ganglia of diabetic organ donors.

Featured Genetics Neuroscience Open Neuroscience Articles

·December 10, 2022·5 min read

Proprioception: Describing the Genes Associated With the Sixth Sense

Study identifies genetic markers in cells associated with proprioception. The findings provide new clues about how proprioceptive sensory neurons help control movement.

Featured Neurology Neuroscience Open Neuroscience Articles

·January 27, 2022·3 min read

Could Long-Dead Bacteria Be the Culprit Behind Lingering Lyme Symptoms?

The remnants of the Lyme causing B. burgdorferi bacteria may be responsible for the neuroinflammation associated with long-term Lyme disease symptoms. Researchers say the remnants are more inflammatory than the live bacteria.

This shows a boy drinking from a water bottle

Featured Neuroscience

·January 27, 2022·5 min read

How Gut Neurons Communicate With the Brain to Control Thirst

A new study sheds light on the gut-to-brain osmolality signaling that regulates thirst, revealing a sensory pathway that mediates the process.

This shows a woman clutching her tummy in pain

Featured Genetics Neurology Open Neuroscience Articles Pain

·April 9, 2021·3 min read

Higher Rates of Chronic Pain in Women Linked to Genetics

Genetics may help explain why women are at higher risk for developing chronic pain disorders than men. The study also sheds light on the role the central nervous system plays in the development of chronic pain.

Featured Neuroscience Open Neuroscience Articles

·August 22, 2019·4 min read

Scratching the surface of how your brain senses an itch

Researchers identified a set of neurons in the spinal cord that transmits a light-touch signal from the skin to the brain. NPY-Y1 signaling regulates the transmission of innocuous tactile information by establishing thresholds for touch discrimination and mechanical itch reflexes. The findings shed new light on the neurobiological basis of chronic itching.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·July 13, 2019·3 min read

An itch to scratch: Potential approach to chronic itch problem identified

Blocking the NPR1 receptor on the spinal cords of mice and humans may help reduce chronic itching.

Featured Genetics Neurology Open Neuroscience Articles Pain

·November 24, 2017·4 min read

New Avenue For Drug Treatment in Neuropathic Pain

Blocking dorsal root ganglion pain neurons from releasing microRNA-21 has an anti-inflammatory effect at the cellular level, preventing neuropathic pain, researchers report.