The remnants of the Lyme causing B. burgdorferi bacteria may be responsible for the neuroinflammation associated with long-term Lyme disease symptoms. Researchers say the remnants are more inflammatory than the live bacteria.
A new study sheds light on the gut-to-brain osmolality signaling that regulates thirst, revealing a sensory pathway that mediates the process.
Genetics may help explain why women are at higher risk for developing chronic pain disorders than men. The study also sheds light on the role the central nervous system plays in the development of chronic pain.
Researchers identified a set of neurons in the spinal cord that transmits a light-touch signal from the skin to the brain. NPY-Y1 signaling regulates the transmission of innocuous tactile information by establishing thresholds for touch discrimination and mechanical itch reflexes. The findings shed new light on the neurobiological basis of chronic itching.
Blocking the NPR1 receptor on the spinal cords of mice and humans may help reduce chronic itching.
Blocking dorsal root ganglion pain neurons from releasing microRNA-21 has an anti-inflammatory effect at the cellular level, preventing neuropathic pain, researchers report.
A new study reports on how sensory neurons work together to transmit itch signals from the skin, via the spinal cord and to the brain.
A new study of touch and movement could benefit people with movement disorders and improve the design of new robotics.
The carnage evident in disasters like car wrecks or wartime battles is oftentimes mirrored within the bodies of the people...
