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depression

This shows two heads, one shows symbols of diminished rewards, the other an abundance of rewards.

·February 14, 2026·7 min read

How the Brain Distinguishes Instant Treats from Long-Term Triumphs

Is your brain chasing a reward or checking off a goal? Scientists have found a specific electrical signal that could explain why depression dulls pleasure and how to fix it.

Featured Neuroscience Psychology

·December 18, 2025·7 min read

Depression Quietly Damages the Heart Through Stress Circuits

Depression and anxiety may heighten cardiovascular disease risk through chronic stress pathways in the brain and body. In a large analysis of more than 85,000 adults, those with depression or anxiety — especially both — were significantly more likely to experience heart attack, stroke or heart failure.

Neuroscience

·December 10, 2025·7 min read

Anti-Inflammatory Treatments Show Promise for Depression

A new analysis shows that anti-inflammatory medications may help reduce symptoms for a subset of people with depression who also have chronic, low-grade inflammation. By reviewing randomized controlled trials that specifically enrolled individuals with elevated inflammatory markers, researchers found that anti-inflammatory treatments significantly reduced both overall depressive symptoms and anhedonia.

This shows an angry man, a crying woman and a brain.

Featured Neuroscience Psychology

·December 2, 2025·5 min read

Abuse Survivors Show Unique Injury Signatures Tied to Suicide Risk

A new study finds that victims of intimate partner violence who also experience suicidal thoughts or behaviors show distinct and severe injury patterns on medical imaging. These patients were far more likely to present at night in emergency settings and had dramatically higher rates of head, spinal, and deep internal injuries.

Featured Genetics Neuroscience Psychology

·November 24, 2025·9 min read

Genetics Point to a New Type of Suicide Risk

New research shows that many people who die by suicide without prior suicidal thoughts or behaviors are not simply “missed cases”—they may have an entirely different underlying risk profile. Genetic analyses of more than 2,700 deaths revealed that these individuals carry fewer genetic risk factors for major psychiatric conditions compared to those with known suicidality.

Featured Neuroscience Psychology

·November 24, 2025·4 min read

Stress-Like Behaviors Traced to a Single ATP Circuit in the Brain

New research reveals that reduced ATP signaling in the hippocampus plays a causal role in both depression- and anxiety-like behaviors. In stressed male mice, ATP levels and the ATP-releasing protein connexin 43 were markedly lower.

This shows a woman's head an a lightening bolt.

Featured Neuroscience Psychology

·November 19, 2025·6 min read

Shocking Disparities: Women Face Higher Risk of ECT

A large international survey of 858 electroconvulsive therapy recipients found that women are twice as likely as men to receive ECT and experience more adverse effects. Women reported higher rates of memory loss, greater feelings of coercion, and more harmful emotional outcomes, often describing the treatment as retraumatizing.

Featured Neuroscience Psychology

·November 18, 2025·7 min read

Deep Brain Stimulation Promising for Severe, Resistant Depression

A new clinical trial shows that deep brain stimulation (DBS) improved symptoms in half of adults with treatment-resistant depression, with one-third reaching remission. Researchers found that theta-frequency brain activity in the bed nucleus of the stria terminalis (BNST) predicted how well each patient responded.

Featured Genetics Neuroscience

·November 14, 2025·5 min read

Genetic Roots of Depression Reveal Strong Suicide Risk Signals

New research shows that depression beginning before age 25 has a much stronger hereditary component than depression that emerges later in life. By analyzing genetic data from over 150,000 people with depression, researchers identified distinct genetic regions linked specifically to early-onset cases.

This shows a woman sitting in a dark room.

Featured Neuroscience Psychology

·November 2, 2025·4 min read

Don’t Ignore the Winter Blues, It Could Be Seasonal Depression

As daylight fades, many experience fatigue or low mood—but for millions, these symptoms signal seasonal affective disorder (SAD), a serious form of depression. Reduced sunlight disrupts serotonin, melatonin, and the body’s circadian rhythm, leading to feelings of hopelessness, loss of interest, and sleep or appetite changes.

Featured Neuroscience Psychology

·October 30, 2025·6 min read

Common Antidepressant Eases Core Symptoms Within Two Weeks

A new analysis of the PANDA clinical trial reveals that sertraline, one of the most prescribed antidepressants, improves key emotional symptoms of depression—such as sadness, self-loathing, and suicidal thoughts—within just two weeks of treatment. Using network analysis to assess individual symptoms, researchers found that the drug also eased anxiety early on, while somatic effects like fatigue and low libido appeared but later stabilized.

This shows a child surrounded by bacteria.

Featured Neuroscience Psychology

·October 30, 2025·6 min read

Toddler Gut Bacteria Linked to Childhood Anxiety and Depression

A new study suggests that a child’s gut microbiome at age 2 may influence their emotional health years later. Researchers found that higher levels of bacteria from the Clostridiales order and Lachnospiraceae family were linked to stronger connectivity across emotion-related brain networks and a higher risk of anxiety and depression symptoms by age 7½.

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depression

How the Brain Distinguishes Instant Treats from Long-Term Triumphs

Depression Quietly Damages the Heart Through Stress Circuits

Anti-Inflammatory Treatments Show Promise for Depression

Abuse Survivors Show Unique Injury Signatures Tied to Suicide Risk

Genetics Point to a New Type of Suicide Risk

Stress-Like Behaviors Traced to a Single ATP Circuit in the Brain

Shocking Disparities: Women Face Higher Risk of ECT

Deep Brain Stimulation Promising for Severe, Resistant Depression

Genetic Roots of Depression Reveal Strong Suicide Risk Signals

Don’t Ignore the Winter Blues, It Could Be Seasonal Depression

Common Antidepressant Eases Core Symptoms Within Two Weeks

Toddler Gut Bacteria Linked to Childhood Anxiety and Depression

Mapping the Brain’s Resting Grid Through Menopause

Parental Infertility Biology, Not IVF, Linked to Child Autism Traits

Glucosamine Supplement Linked to Accelerated Alzheimer’s Progression

Silencing One Brain Gene May Reverse Autism Deficits

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