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depression

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·November 2, 2025·4 min read

Don’t Ignore the Winter Blues, It Could Be Seasonal Depression

As daylight fades, many experience fatigue or low mood—but for millions, these symptoms signal seasonal affective disorder (SAD), a serious form of depression. Reduced sunlight disrupts serotonin, melatonin, and the body’s circadian rhythm, leading to feelings of hopelessness, loss of interest, and sleep or appetite changes.

Featured Neuroscience Psychology

·October 30, 2025·6 min read

Common Antidepressant Eases Core Symptoms Within Two Weeks

A new analysis of the PANDA clinical trial reveals that sertraline, one of the most prescribed antidepressants, improves key emotional symptoms of depression—such as sadness, self-loathing, and suicidal thoughts—within just two weeks of treatment. Using network analysis to assess individual symptoms, researchers found that the drug also eased anxiety early on, while somatic effects like fatigue and low libido appeared but later stabilized.

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Featured Neuroscience Psychology

·October 30, 2025·6 min read

Toddler Gut Bacteria Linked to Childhood Anxiety and Depression

A new study suggests that a child’s gut microbiome at age 2 may influence their emotional health years later. Researchers found that higher levels of bacteria from the Clostridiales order and Lachnospiraceae family were linked to stronger connectivity across emotion-related brain networks and a higher risk of anxiety and depression symptoms by age 7½.

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Featured Genetics Neuroscience Psychology

·October 29, 2025·8 min read

$2 Saliva Test Could Help Detect Depression and Schizophrenia

Scientists have developed a portable biosensor that can detect levels of BDNF, a protein linked to mental health conditions such as depression, schizophrenia, and bipolar disorder. The flexible, low-cost device analyzes a drop of saliva in under three minutes, offering a fast, affordable, and noninvasive diagnostic tool.

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Featured Neuroscience Psychology

·October 26, 2025·6 min read

Music and Nature Work in Harmony to Ease Stress and Lift Mood

The viral phrase “touch grass” may be more than internet humor—science shows that engaging with nature and music can significantly boost emotional and physical well-being. A new review found that combining these experiences—such as listening to music outdoors, gardening while singing, or caring for animals—can improve mood, reduce stress, and ease symptoms of anxiety and depression.

Featured Neuroscience Psychology

·October 22, 2025·8 min read

Ketamine Fails to Outperform Placebo in Major Depression Trial

A large randomized and blinded clinical trial has found no additional benefit of repeated ketamine infusions over standard inpatient care for treating major depression. The study compared ketamine with a psychoactive placebo and found no meaningful differences in objective or self-reported depression scores, cognition, or quality of life.

Featured Neuroscience Psychology

·October 8, 2025·5 min read

Reelin Shows Promise for Healing Both Gut and Depression

A new study reveals that the protein Reelin may hold the key to treating both “leaky gut” and major depressive disorder. Chronic stress lowers Reelin levels in the gut, weakening the intestinal barrier and allowing toxins to trigger inflammation that worsens depression.

This shows a brain wrapped in a chain and a depressed woman.

Featured Neuroscience Psychology

·October 3, 2025·6 min read

Sugar Chains in the Brain: New Pathway Behind Depression Found

Scientists have discovered that depression can be driven by abnormal sugar modifications on proteins in the brain, offering a new molecular pathway for understanding the disorder. Chronic stress was shown to reduce sialylation—a stabilizing sugar process—in the prefrontal cortex, impairing neural circuit stability and triggering depressive symptoms.

Featured Neurology Neuroscience Pain Psychology

·October 2, 2025·6 min read

Psilocybin Rewire Brain Circuits Tied to Pain and Mood

New research shows that psilocybin, the active compound in psychedelic mushrooms, can reduce both chronic pain and pain-related depression by modulating brain circuits rather than acting at the site of injury. In mouse studies, a single dose provided pain relief and mood benefits lasting nearly two weeks by targeting the anterior cingulate cortex.

This shows a woman drinking soda and a shadow of a woman.

Featured Neuroscience Psychology

·September 24, 2025·5 min read

Sugary Drinks Linked to Depression Through Gut Microbiome

A new study shows that sugary drinks don’t just affect physical health—they may also raise the risk of depression in women by disrupting the gut microbiome. Researchers found that high consumption of soft drinks was linked to both a greater likelihood of major depressive disorder and more severe symptoms, particularly among women.

This shows a woman's face and network lines.

Featured Neuroscience Psychology

·September 16, 2025·4 min read

AI Spots Subtle Facial Cues Linked to Early Depression Risk

Depression’s earliest signs can be hard to spot, but a new study shows AI can detect them in subtle facial movements. Japanese students with subthreshold depression were perceived as less friendly and expressive by peers, despite not seeming nervous or fake.

Featured Neuroscience Psychology

·September 15, 2025·4 min read

Simple Hair Test May Spot Mental Health Risks in Kids

Long-term stress, measured through hair cortisol, may help predict mental health risks in children living with chronic physical illnesses. In a four-year study of 244 children, researchers found that persistently high cortisol levels were strongly linked to anxiety, depression, and behavioral difficulties.

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depression

Don’t Ignore the Winter Blues, It Could Be Seasonal Depression

Common Antidepressant Eases Core Symptoms Within Two Weeks

Toddler Gut Bacteria Linked to Childhood Anxiety and Depression

$2 Saliva Test Could Help Detect Depression and Schizophrenia

Music and Nature Work in Harmony to Ease Stress and Lift Mood

Ketamine Fails to Outperform Placebo in Major Depression Trial

Reelin Shows Promise for Healing Both Gut and Depression

Sugar Chains in the Brain: New Pathway Behind Depression Found

Psilocybin Rewire Brain Circuits Tied to Pain and Mood

Sugary Drinks Linked to Depression Through Gut Microbiome

AI Spots Subtle Facial Cues Linked to Early Depression Risk

Simple Hair Test May Spot Mental Health Risks in Kids

BrainSTEM Atlas Maps Every Cell of the Developing Human Brain

Your Brain Knows a Viral Message Before You Do

Antioxidant Defense System in the Brain Discovered

Long-Term Melatonin Use Linked to Higher Heart Failure Risk

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