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depression

Featured Genetics Neuroscience Psychology

·November 24, 2025·9 min read

Genetics Point to a New Type of Suicide Risk

New research shows that many people who die by suicide without prior suicidal thoughts or behaviors are not simply “missed cases”—they may have an entirely different underlying risk profile. Genetic analyses of more than 2,700 deaths revealed that these individuals carry fewer genetic risk factors for major psychiatric conditions compared to those with known suicidality.

Featured Neuroscience Psychology

·November 24, 2025·4 min read

Stress-Like Behaviors Traced to a Single ATP Circuit in the Brain

New research reveals that reduced ATP signaling in the hippocampus plays a causal role in both depression- and anxiety-like behaviors. In stressed male mice, ATP levels and the ATP-releasing protein connexin 43 were markedly lower.

This shows a woman's head an a lightening bolt.

Featured Neuroscience Psychology

·November 19, 2025·6 min read

Shocking Disparities: Women Face Higher Risk of ECT

A large international survey of 858 electroconvulsive therapy recipients found that women are twice as likely as men to receive ECT and experience more adverse effects. Women reported higher rates of memory loss, greater feelings of coercion, and more harmful emotional outcomes, often describing the treatment as retraumatizing.

Featured Neuroscience Psychology

·November 18, 2025·7 min read

Deep Brain Stimulation Promising for Severe, Resistant Depression

A new clinical trial shows that deep brain stimulation (DBS) improved symptoms in half of adults with treatment-resistant depression, with one-third reaching remission. Researchers found that theta-frequency brain activity in the bed nucleus of the stria terminalis (BNST) predicted how well each patient responded.

Featured Genetics Neuroscience

·November 14, 2025·5 min read

Genetic Roots of Depression Reveal Strong Suicide Risk Signals

New research shows that depression beginning before age 25 has a much stronger hereditary component than depression that emerges later in life. By analyzing genetic data from over 150,000 people with depression, researchers identified distinct genetic regions linked specifically to early-onset cases.

This shows a woman sitting in a dark room.

Featured Neuroscience Psychology

·November 2, 2025·4 min read

Don’t Ignore the Winter Blues, It Could Be Seasonal Depression

As daylight fades, many experience fatigue or low mood—but for millions, these symptoms signal seasonal affective disorder (SAD), a serious form of depression. Reduced sunlight disrupts serotonin, melatonin, and the body’s circadian rhythm, leading to feelings of hopelessness, loss of interest, and sleep or appetite changes.

Featured Neuroscience Psychology

·October 30, 2025·6 min read

Common Antidepressant Eases Core Symptoms Within Two Weeks

A new analysis of the PANDA clinical trial reveals that sertraline, one of the most prescribed antidepressants, improves key emotional symptoms of depression—such as sadness, self-loathing, and suicidal thoughts—within just two weeks of treatment. Using network analysis to assess individual symptoms, researchers found that the drug also eased anxiety early on, while somatic effects like fatigue and low libido appeared but later stabilized.

This shows a child surrounded by bacteria.

Featured Neuroscience Psychology

·October 30, 2025·6 min read

Toddler Gut Bacteria Linked to Childhood Anxiety and Depression

A new study suggests that a child’s gut microbiome at age 2 may influence their emotional health years later. Researchers found that higher levels of bacteria from the Clostridiales order and Lachnospiraceae family were linked to stronger connectivity across emotion-related brain networks and a higher risk of anxiety and depression symptoms by age 7½.

This shows a cell phone, neurons and a sensor.

Featured Genetics Neuroscience Psychology

·October 29, 2025·8 min read

$2 Saliva Test Could Help Detect Depression and Schizophrenia

Scientists have developed a portable biosensor that can detect levels of BDNF, a protein linked to mental health conditions such as depression, schizophrenia, and bipolar disorder. The flexible, low-cost device analyzes a drop of saliva in under three minutes, offering a fast, affordable, and noninvasive diagnostic tool.

This shows a woman meditating in a field.

Featured Neuroscience Psychology

·October 26, 2025·6 min read

Music and Nature Work in Harmony to Ease Stress and Lift Mood

The viral phrase “touch grass” may be more than internet humor—science shows that engaging with nature and music can significantly boost emotional and physical well-being. A new review found that combining these experiences—such as listening to music outdoors, gardening while singing, or caring for animals—can improve mood, reduce stress, and ease symptoms of anxiety and depression.

Featured Neuroscience Psychology

·October 22, 2025·8 min read

Ketamine Fails to Outperform Placebo in Major Depression Trial

A large randomized and blinded clinical trial has found no additional benefit of repeated ketamine infusions over standard inpatient care for treating major depression. The study compared ketamine with a psychoactive placebo and found no meaningful differences in objective or self-reported depression scores, cognition, or quality of life.

Featured Neuroscience Psychology

·October 8, 2025·5 min read

Reelin Shows Promise for Healing Both Gut and Depression

A new study reveals that the protein Reelin may hold the key to treating both “leaky gut” and major depressive disorder. Chronic stress lowers Reelin levels in the gut, weakening the intestinal barrier and allowing toxins to trigger inflammation that worsens depression.

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depression

Genetics Point to a New Type of Suicide Risk

Stress-Like Behaviors Traced to a Single ATP Circuit in the Brain

Shocking Disparities: Women Face Higher Risk of ECT

Deep Brain Stimulation Promising for Severe, Resistant Depression

Genetic Roots of Depression Reveal Strong Suicide Risk Signals

Don’t Ignore the Winter Blues, It Could Be Seasonal Depression

Common Antidepressant Eases Core Symptoms Within Two Weeks

Toddler Gut Bacteria Linked to Childhood Anxiety and Depression

$2 Saliva Test Could Help Detect Depression and Schizophrenia

Music and Nature Work in Harmony to Ease Stress and Lift Mood

Ketamine Fails to Outperform Placebo in Major Depression Trial

Reelin Shows Promise for Healing Both Gut and Depression

Smelling Fatty Foods in Pregnancy May Raise Obesity Risk in Children

AI Watches Pianists and Reconstructs Their Muscle Signals

Scientists Achieve Sustained HIV Control Without Lifelong Drugs

Insomnia Keeps the Brain Stuck in Daytime Mode

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